Document Detail

Tuberculous meningitis in pregnancy--implications for mother and fetus: case report and literature review.
MedLine Citation:
PMID:  10582863     Owner:  NLM     Status:  MEDLINE    
The objective of this article is to report an illustrative case of tuberculous meningitis in pregnancy and review the recent literature outlining management and outcome of this devastating disease. A MEDLINE database search for English and French language articles dating back to 1966 was conducted and supplemented by reviewing the references of key articles and textbooks. An article was included if it described a case of tuberculous meningitis during pregnancy or explained the management of this disease. The search yielded a total of 17 articles, case reports, and reviews relating to tuberculous meningitis and/or pregnancy. Six authors describe cases and outcomes of tuberculous meningitis during pregnancy to give a total of 55 cases. Twenty-one patients died of their disease (38.2%), while 15 fetal or neonatal deaths have been reported (36.6%). Tuberculous meningitis is an insidious disease presenting a diagnostic challenge to even an astute practitioner. When recognized early and treated effectively with modern antituberculous medication, prognosis for mother and child is greatly improved.
M R Prévost; K M Fung Kee Fung
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of maternal-fetal medicine     Volume:  8     ISSN:  1057-0802     ISO Abbreviation:  J Matern Fetal Med     Publication Date:    1999 Nov-Dec
Date Detail:
Created Date:  2000-01-07     Completed Date:  2000-01-07     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  9211288     Medline TA:  J Matern Fetal Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  289-94     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Ottawa, Ottawa Hospital, Ontario, Canada.
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MeSH Terms
Anti-Bacterial Agents
Antitubercular Agents / analysis,  therapeutic use
Delivery, Obstetric
Drug Therapy, Combination / therapeutic use
Infant, Newborn
Magnetic Resonance Imaging
Milk, Human / chemistry
Pregnancy Complications, Infectious / cerebrospinal fluid,  diagnosis,  therapy*
Tuberculosis, Meningeal / cerebrospinal fluid,  diagnosis,  therapy*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Antitubercular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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