Document Detail


Tuberculosis in patients with systemic lupus erythematosus.
MedLine Citation:
PMID:  11229272     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a retrospective analysis of 146 systemic lupus erythematosus (SLE) patients seen over a 5 year period, 17 patients of tuberculosis (TB) were identified yielding a prevalence rate of 11.6%. The median duration of SLE was 12 months (range 2-96 months) and 12/17 patients had disease activity score of more than five. The median duration of steroid treatment was 12 months (range 0-96 months) and the median cummulative dose of steroid was 7.75 gms (range 0-22.1 gms). Pulmonary TB (miliary-5, nonmiliary infiltrates-7 and pleural effusion-2) was the commonest type and there was an average diagnostic delay of approximately 1 month. While, majority of the patients responded adequately to treatment, 1 patient had a relapse and 1 expired due to a combination of active lupus and disseminated TB. Only 1 patient had received prophylactic isoniazid.
Authors:
C Balakrishnan; G Mangat; G Mittal; V R Joshi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the Association of Physicians of India     Volume:  46     ISSN:  0004-5772     ISO Abbreviation:  J Assoc Physicians India     Publication Date:  1998 Aug 
Date Detail:
Created Date:  2001-03-02     Completed Date:  2001-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505585     Medline TA:  J Assoc Physicians India     Country:  India    
Other Details:
Languages:  eng     Pagination:  682-3     Citation Subset:  IM    
Affiliation:
Rheumatology Unit, PD Hinduja Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai-400 016.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Antitubercular Agents / therapeutic use
Female
Humans
India / epidemiology
Lupus Erythematosus, Systemic / complications*
Male
Middle Aged
Prevalence
Retrospective Studies
Tuberculosis, Pulmonary / complications*,  drug therapy,  epidemiology
Chemical
Reg. No./Substance:
0/Antitubercular Agents
Comments/Corrections
Comment In:
J Assoc Physicians India. 1999 Jul;47(7):747   [PMID:  10778609 ]
J Assoc Physicians India. 1999 Jul;47(7):747-8   [PMID:  10778610 ]

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