| Tuberculosis and AIDS co-morbidity in children: linkage of databases from espirito santo state, Brazil. | |
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MedLine Citation:
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PMID: 20876684 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We assessed the prevalence of AIDS among children diagnosed with active tuberculosis (TB) in Espírito Santo State, Brazil, by linking TB and AIDS surveillance databases using Reclink software and SPSS. Among 411 pediatric TB cases from 2000 to 2006, 27 (7%) were co-infected with AIDS. Most children were unable to provide a sputum specimen; co-infected patients were more likely to be smear negative for acid-fast bacilli (83% vs 46%; p = 0.07) and culture positive for Mycobacterium tuberculosis (44% vs 19%; p < 0.001). In all, 57% of co-infected patients did not react to tuberculin skin test compared with 17% of TB patients (p < 0.001). This report emphasizes the significance of AIDS in pediatric TB cases and highlights the importance of evaluating surveillance databases for gaining a better understanding of the burden of co-infection. |
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Authors:
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Angelica E Miranda; Reynaldo Dietze; Ethel L Maciel; Thiago N Prado; Antonio L Caus; Murilo M Silva; Jonathan E Golub |
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Publication Detail:
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Type: Journal Article Date: 2010-09-28 |
Journal Detail:
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Title: Journal of tropical pediatrics Volume: 57 ISSN: 1465-3664 ISO Abbreviation: J. Trop. Pediatr. Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-07-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8010948 Medline TA: J Trop Pediatr Country: England |
Other Details:
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Languages: eng Pagination: 296-8 Citation Subset: IM |
Affiliation:
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Universidade Federal do Espirito Santo (UFES), Núcleo de Doenças Infecciosas (NDI), Vitoria, Brazil. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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