Document Detail


Tryptophan-transducing bacteriophages: in vitro studies with restriction endonucleases HindII + III and Escherichia coli ribonucleic acid polymerase.
MedLine Citation:
PMID:  334724     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The HindII + III restriction enzyme fragmentation pattern of various lambda-phi80trp deoxyribonucleic acid molecules is presented. An analysis of deoxyribonucleic acid molecules carrying deletions ending within the trp regulatory elements and a deoxyribonucleic acid molecule carrying a deletion within trpE indicates that a fragment of 8.3 X 10(5) daltons contains at least part of the trp promoter, the entire trp leader region, and part of the trpE gene. The observation that ribonucleic acid polymerase, when present in the HindII + III digestion mixture, results in the fusion of this 8.3 X 10(5)-dalton fragment to the preceding bacterial fragment suggests that HindII + III cuts within trpP.
Authors:
B B Jones; W S Reznikoff
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of bacteriology     Volume:  132     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  270-81     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Coliphages / analysis,  genetics*,  metabolism
DNA Restriction Enzymes / metabolism
DNA, Viral / genetics*,  metabolism
DNA-Directed RNA Polymerases / metabolism
Escherichia coli / enzymology
Molecular Weight
Operon*
Protein Binding
Transduction, Genetic*
Tryptophan / biosynthesis,  genetics*
Chemical
Reg. No./Substance:
0/DNA, Viral; 73-22-3/Tryptophan; EC 2.7.7.6/DNA-Directed RNA Polymerases; EC 3.1.21.-/DNA Restriction Enzymes
Comments/Corrections

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