| Trypanocidal effects of curcumin in vitro. | |
| | |
MedLine Citation:
|
PMID: 9657056 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
During the course of study searching for the antiparasitic agents from natural compounds, we found that curcumin showed cytotoxicity against African trypanosomes in vitro. The LD50 values of curcumin were 4.77 +/- 0.91 microM for bloodstream forms and 46.52 +/- 4.94 microM for procyclic forms of Trypanosoma brucei brucei (GUTat 3.1 clone). |
| | |
Authors:
|
M Nose; T Koide; Y Ogihara; Y Yabu; N Ohta |
Related Documents
:
|
2238836 - Identification of irradiated foods by the thermoluminescence of mineral contamination. 15381086 - Stabilization of alanine substituted p53 protein at ser15, thr18, and ser20 in response... 11863716 - Observation of the color-suppressed decay b( 0)-->d(0)pi(0). 11472166 - Ice-catalyzed ionization of hydrochloric acid. 8693216 - Salt and public health--policies for dietary salt in the nordic countries. 3696196 - Total mercury and its distribution in blue crab and deep water pink shrimp from alexand... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Biological & pharmaceutical bulletin Volume: 21 ISSN: 0918-6158 ISO Abbreviation: Biol. Pharm. Bull. Publication Date: 1998 Jun |
Date Detail:
|
Created Date: 1998-09-04 Completed Date: 1998-09-04 Revised Date: 2003-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 9311984 Medline TA: Biol Pharm Bull Country: JAPAN |
Other Details:
|
Languages: eng Pagination: 643-5 Citation Subset: IM |
Affiliation:
|
Department of Pharmacognosy and Plant Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Curcumin / pharmacology* Mice Trypanocidal Agents / pharmacology* Trypanosoma brucei brucei / drug effects* |
| Chemical | |
Reg. No./Substance:
|
0/Trypanocidal Agents; 458-37-7/Curcumin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Anthraquinones from Neonauclea calycina and their inhibitory activity against DNA topoisomerase II.
Next Document: Effect of guarana on exercise in normal and epinephrine-induced glycogenolytic mice.