Document Detail

True multifood allergy in a 4-year-old child: a case study.
MedLine Citation:
PMID:  12464167     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Food allergy is quite common in children, but it usually trends to improve with ageing. When an individual has specific IgE to a large variety of foods (multifood allergy) the clinical picture may be of remarkable severity and the avoidance of the offending foods may lead to severe dietary impairment. We describe a case of a child with ascertained multifood allergy. METHODS: The prick-by-prick testing with fresh foods and serum IgE tests were used to evaluate the patient's sensitivity to food allergens. The clinical effect of sensitizations were evaluated by DBPCFC which was carried out for egg, fish, peanuts, walnut, fig, asparagus, orange, chicory, medlar, peach, strawberry and cherry. Each challenge was performed on a separate day. Medical assistance and resuscitation facilities were available during the whole challenge procedures. RESULTS: SPT with fresh food gave a 4 mm wheal for fig, asparagus, cherry and walnut; a 5 mm wheal for medlar and orange; a 6 mm wheal for chicory and strawberry; a 7 mm wheal for fish and peanuts; an 8 mm wheal for peach and a 9 mm wheal for egg. The RAST assay confirmed the presence of specific IgE to egg, fish, peanuts, walnut, fig, orange, strawberry, peach, and cherry. The total serum IgE was 730,6 kU/l.The DBPCFC was positive, at various degrees, for all foods tested according to skin sensitizations. CONCLUSIONS: The case herein described is a true multifood allergy, as confirmed by the DBPCFC. Multifood allergy is not common, but when present it can lead to severe dietary limitation.
G B Pajno; G Passalacqua; S La Grutta; D Vita; R Feliciotto; S Parmiani; G Barberio
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Allergologia et immunopathologia     Volume:  30     ISSN:  0301-0546     ISO Abbreviation:  Allergol Immunopathol (Madr)     Publication Date:    2002 Nov-Dec
Date Detail:
Created Date:  2002-12-04     Completed Date:  2003-03-17     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  0370073     Medline TA:  Allergol Immunopathol (Madr)     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  338-41     Citation Subset:  IM    
II Pediatric Division. University Hospital. Messina. Italy.
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MeSH Terms
Allergens / diagnostic use
Antibody Specificity
Arachis hypogaea / adverse effects,  immunology
Asthma / etiology
Child, Preschool
Eggs / adverse effects
Fishes / immunology
Food Hypersensitivity / etiology*
Fruit / adverse effects,  immunology
Gastroenteritis / etiology
Immunoglobulin E / blood,  immunology*
Nuts / adverse effects,  immunology
Seafood / adverse effects
Skin Tests
Urticaria / etiology
Vegetables / adverse effects,  immunology
Reg. No./Substance:
0/Allergens; 37341-29-0/Immunoglobulin E

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