Document Detail


Troponin-T as a serum marker for myocardial infarction.
MedLine Citation:
PMID:  9138099     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report here our experience with serum troponin T (TnT), measured with the sandwich immunoassay introduced by Boehringer Mannheim as a marker for myocardial infarction. We assayed TnT in serial serum samples from 30 patients with time courses of serum CK, CK-MB, AST, and LD that we consider typical of acute myocardial infarction (MI). In every patient but one, TnT rose in parallel with both CK-MB and AST, but remained elevated significantly longer. The ratios of the elevations of the different markers varied from patient to patient with marked variation in the ratio of TnT to CK-MB. There appeared to be a significant association between the magnitude of that ratio with the level of ALT.
Authors:
V V Murthy; A Karmen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of clinical laboratory analysis     Volume:  11     ISSN:  0887-8013     ISO Abbreviation:  J. Clin. Lab. Anal.     Publication Date:  1997  
Date Detail:
Created Date:  1997-06-23     Completed Date:  1997-06-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8801384     Medline TA:  J Clin Lab Anal     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  125-8     Citation Subset:  IM    
Affiliation:
Department of Laboratory Medicine, Albert Einstein College of Medicine, The Bronx, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Aspartate Aminotransferases / blood
Biological Markers / blood*
Creatine Kinase / blood
Humans
Immunoassay / methods
Isoenzymes
L-Lactate Dehydrogenase / blood
Myocardial Infarction / blood*
Reference Values
Reproducibility of Results
Troponin / blood*
Troponin T
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Isoenzymes; 0/Troponin; 0/Troponin T; EC 1.1.1.27/L-Lactate Dehydrogenase; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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