Document Detail


Trophoblastic embolization during molar evacuation: central hemodynamic observations.
MedLine Citation:
PMID:  3822283     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated prospectively the extent of trophoblastic embolization and its central hemodynamic effects during and after evacuation of large molar pregnancies in six women. A pulmonary artery catheter was inserted to obtain hemodynamic measurements as well as to obtain blood samples to identify trophoblasts before, during, and six hours after evacuation. Small numbers of both multinucleated giant cells and of large mononuclear cells with abundant cytoplasm were identified in the buffy coat of blood, aspirated in two cases before evacuation and for all six cases, during evacuation. There were no significant changes in heart rate or mean systemic arterial, pulmonary arterial, central venous, and pulmonary capillary wedge pressures; or cardiac output, stroke volume, and pulmonary or systemic vascular resistance when preevacuation preanesthetic values were compared with those six hours after evacuation. However, significant decreases in heart rate, mean arterial pressure, and pulmonary vascular resistance were observed during evacuation, which returned to preevacuation levels by completion of anesthesia.
Authors:
G D Hankins; G D Wendel; R R Snyder; F G Cunningham
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  69     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1987 Mar 
Date Detail:
Created Date:  1987-03-30     Completed Date:  1987-03-30     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  368-72     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Female
Hemodynamics
Humans
Hydatidiform Mole / surgery*
Hysterectomy
Intraoperative Care
Intraoperative Complications / etiology
Monitoring, Physiologic
Postoperative Complications / etiology
Pregnancy
Prospective Studies
Pulmonary Embolism / etiology*
Risk
Trophoblasts*
Uterine Neoplasms / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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