Document Detail

Trophoblast membrane infusion for unexplained recurrent miscarriage.
MedLine Citation:
PMID:  3382607     Owner:  NLM     Status:  MEDLINE    
A novel protocol is described which has been developed for immunotherapy in unexplained recurrent miscarriage. This is based on a single intravenous infusion with isolated placental trophoblast plasma membrane vesicle preparations. Clinical experience gained with this approach is described. A total of 16/21 (76%) patients who subsequently had pregnancies have now achieved a live birth or are currently pregnant at greater than 28 weeks gestation.
P M Johnson; K V Chia; C A Hart; H B Griffith; W J Francis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  95     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-08-11     Completed Date:  1988-08-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  342-7     Citation Subset:  AIM; IM    
Department of Immunology, University of Liverpool, UK.
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MeSH Terms
Abortion, Habitual / prevention & control*
Antigens, Surface / administration & dosage
Cell Membrane / immunology
Immunization / methods*
Trophoblasts / immunology*
Reg. No./Substance:
0/Antigens, Surface

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