Document Detail

Tropheryma whipplei endocarditis without gastrointestinal involvement.
MedLine Citation:
PMID:  22499804     Owner:  NLM     Status:  MEDLINE    
Whipple's disease, caused by the bacterium Tropheryma whipplei, is a rare chronic multi-system illness commonly affecting the gastrointestinal (GI) tract and presenting with a triad of diarrhoea, weight loss and malabsorption. While 20-55% of patients with a diagnosis of Whipple's disease have clinically evident cardiac manifestations, the initial presentation with isolated valvular disease, without any GI symptoms, is rare. Whereas cardiac involvement usually involves a single valve, cases of double-valve involvement are extremely rare. We report the case of a patient with T. whipplei native aortic and mitral valvular endocarditis, without GI involvement, who presented with the new-onset cardiac failure and ventricular arrhythmias, which required urgent double-valve replacement. This case report is accompanied by a review of the relevant literature.
Susannah M Love; Lindsay Morrison; Clare Appleby; Paul Modi
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2012-04-11
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  15     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-06-22     Completed Date:  2012-10-29     Revised Date:  2013-07-02    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  161-3     Citation Subset:  IM    
Liverpool Heart and Chest Hospital, Liverpool, UK.
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MeSH Terms
Aortic Valve / microbiology*,  surgery
Arrhythmias, Cardiac / microbiology
Endocarditis, Bacterial / diagnosis,  microbiology*,  surgery
Heart Failure / microbiology
Heart Valve Diseases / diagnosis,  microbiology*,  surgery
Heart Valve Prosthesis Implantation
Middle Aged
Mitral Valve / microbiology*,  surgery
Treatment Outcome
Tropheryma / isolation & purification*
Whipple Disease / diagnosis,  microbiology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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