Document Detail


Triterpene glycosides from the whole plant of Anemone hupehensis var. japonica and their cytotoxic activity.
MedLine Citation:
PMID:  19952458     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Three new triterpene glycosides (1-3), together with eight known triterpene glycosides (4-11), were isolated from the whole plant of Anemone hupehensis var. japonica (Ranunculaceae). The structures of the new compounds were determined on the basis of spectroscopic analysis and the results of hydrolytic cleavage experiments. The isolated compounds were evaluated for their cytotoxic activities against HL-60 human leukemia cells, HSC-2 human oral squamous carcinoma cells, HSC-4 human oral squamous carcinoma cells, and A549 human lung adenocarcinoma cells.
Authors:
Akihito Yokosuka; Tomoe Sano; Ken Hashimoto; Hiroshi Sakagami; Yoshihiro Mimaki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chemical & pharmaceutical bulletin     Volume:  57     ISSN:  1347-5223     ISO Abbreviation:  Chem. Pharm. Bull.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0377775     Medline TA:  Chem Pharm Bull (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1425-30     Citation Subset:  IM    
Affiliation:
Tokyo University of Pharmacy and Life Sciences, Horinouchi, Hachioji, Japan. yokosuka@toyaku.ac.jp
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