Document Detail

Trisomy 9 in hematologic disorders: possible association with primary thrombocytosis.
MedLine Citation:
PMID:  3472649     Owner:  NLM     Status:  MEDLINE    
Ten patients with a hematologic disorder and a clone of cells with trisomy 9 in the bone marrow were studied in order to investigate the clinical significance of this chromosome anomaly. In five of the patients, trisomy 9 was the only anomaly; in four, there was also trisomy 8; and in one, a Y chromosome was also lacking. Four patients had a myelodysplastic syndrome, and six had a myeloproliferative disorder. Interestingly, four patients had primary thrombocytosis.
D Cournoyer; P Noël; M A Schmidt; G W Dewald
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  27     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1987 Jul 
Date Detail:
Created Date:  1987-07-21     Completed Date:  1987-07-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  73-8     Citation Subset:  IM    
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MeSH Terms
Chromosome Banding
Chromosomes, Human, Pair 9*
Genetic Markers
Middle Aged
Myelodysplastic Syndromes / genetics*
Myeloproliferative Disorders / genetics*
Thrombocytosis / genetics*
Reg. No./Substance:
0/Genetic Markers

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