Document Detail

Trisomy 20 mosaicism confirmed in a phenotypically normal liveborn.
MedLine Citation:
PMID:  2771888     Owner:  NLM     Status:  MEDLINE    
Prenatal diagnosis of trisomy 20 mosaicism in this case was based on cytogenetic analysis of cultured amniotic fluid cells (23/252 cells were trisomy 20 representing cells from each of four primary cultures). The pregnancy continued to term and the mosaicism was confirmed in the phenotypically normal male neonate by analysis of cultured foreskin fibroblasts (7/49 cells + 20) and placental cells 20/20 cells + 20) whereas the peripheral lymphocytes were cytogenetically normal (20/20 cells were 46,XY). This represents the first confirmation of trisomy 20 mosaicism in a phenotypically normal full-term neonate.
J P Park; J B Moeschler; E Rawnsley; S Z Berg; D H Wurster-Hill
Related Documents :
22761708 - Zeb2 mediates multiple pathways regulating cell proliferation, migration, invasion, and...
2844048 - Vulvar paget's disease. cytologic and immunohistologic diagnosis of a case.
16920418 - Time to reconsider saline as the ideal rinsing solution during abdominal surgery.
22902508 - Grape seed proanthocyanidins inhibit migration potential of pancreatic cancer cells by ...
7485458 - Copper transport and kinetics in cultured c6 rat glioma cells.
2109018 - Polyamine-dependent post-translational modification of proteins in differentiating mous...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  9     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-10-03     Completed Date:  1989-10-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  501-4     Citation Subset:  IM    
Dartmouth-Hitchcock Medical Center, Hanover, NH 03756.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chromosomes, Human, Pair 20*
Infant, Newborn*
Comment In:
Prenat Diagn. 1990 Feb;10(2):136-7   [PMID:  2343024 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Rapid sexing of human embryos by non-radioactive in situ hybridization: potential for preimplantatio...
Next Document:  Confirmation of a balanced chromosomal translocation using molecular techniques.