Document Detail


Trisomy 16p in a liveborn infant and a review of partial and full trisomy 16.
MedLine Citation:
PMID:  739528     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An abnormal female infant, who survived for 10 months with almost complete trisomy 16p and monosomy of sub-band 21q22.3, is described. The chromosome anomaly was the result of an unbalanced segregation of a maternal balanced translocation t(16;21)(p11;q22.3). The partial monosomy was considered to have had little or no adverse phenotypic effect. Cases with trisomy of chromosome 16 material are reviewed. It appears that while full trisomy 16 always results in early spontaneous abortion, trisomy 16p or 16q may be compatible with limited postnatal survival.
Authors:
S H Roberts; D P Duckett
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of medical genetics     Volume:  15     ISSN:  0022-2593     ISO Abbreviation:  J. Med. Genet.     Publication Date:  1978 Oct 
Date Detail:
Created Date:  1979-04-25     Completed Date:  1979-04-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985087R     Medline TA:  J Med Genet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  375-81     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chromosomes, Human, 16-18*
Chromosomes, Human, 21-22 and Y
Chromosomes, Human, 6-12 and X
Female
Humans
Infant
Karyotyping
Mosaicism*
Pedigree
Translocation, Genetic
Trisomy*
Comments/Corrections

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