Document Detail

Trismus following treatment of head and neck cancer.
MedLine Citation:
PMID:  21777551     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The aim of this preliminary study was to determine the prevalence of trismus in head and neck cancer patients treated with radiotherapy with or without concomitant chemotherapy and surgery.
METHODS AND MATERIALS: Patients with malignant lesions in the head and neck treated with curative intent were comprehensively evaluated for trismus using subjective and objective measures.
RESULTS: A large proportion of the 70 patients recruited demonstrated moderate to severe subjective trismus (45.7%). Similarly, the vast majority of patients showed slight to severe trismus (91.4%) according to objective secondary outcome measures. Of these patients, 21 (65.6%) were also treated with concurrent chemoradiotherapy. When the radiation field involved the pterygoid muscles, 30 (93.8%) patients reported subjective trismus. Similarly, bilateral pterygoid muscle inclusion resulted in 28 (87.5%) patients with trismus.
CONCLUSIONS: Trismus is a significantly prevalent consequence of treatment for head and neck cancer. Predictive factors include treatment with concurrent chemoradiotherapy and bilateral inclusion of the structures of mastication in the high-dose radiotherapy volume.
Goran Jeremic; Varagur Venkatesan; Abhirami Hallock; Danielle Scott; Alexander Hammond; Nancy Read; Jason Franklin; John Yoo; Kevin Fung
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale     Volume:  40     ISSN:  1916-0216     ISO Abbreviation:  J Otolaryngol Head Neck Surg     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-22     Completed Date:  2012-01-03     Revised Date:  2013-04-10    
Medline Journal Info:
Nlm Unique ID:  101479544     Medline TA:  J Otolaryngol Head Neck Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  323-9     Citation Subset:  IM    
Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON.
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MeSH Terms
Aged, 80 and over
Combined Modality Therapy / adverse effects*
Follow-Up Studies
Head and Neck Neoplasms / therapy*
Middle Aged
Ontario / epidemiology
Retrospective Studies
Risk Factors
Trismus / epidemiology*,  etiology
Young Adult

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