Document Detail

Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms.
MedLine Citation:
PMID:  22270059     Owner:  NLM     Status:  Publisher    
Covering: 1972 to 2011Triptolide, a principal bioactive ingredient of Tripterygium wilfordii Hook F, has attracted extensive exploration due to its unique structure of a diterpenoid triepoxide and multiple biological activities. This review will focus on the structural modifications, structure-activity relationships, pharmacology, and clinical development of triptolide in the last forty years.
Zhao-Li Zhou; Ya-Xi Yang; Jian Ding; Yuan-Chao Li; Ze-Hong Miao
Related Documents :
10672029 - Specificity of the wound-induced leucine aminopeptidase (lap-a) of tomato activity on d...
6804939 - Phosphorylation of synthetic peptides by a tyrosine protein kinase from the particulate...
16522869 - A quantitative assay for aggrecanase activity.
9469909 - New 3d nmr pulse sequences for characterization of polymer chain end structures
9371719 - Cleavage of arginyl-arginine and lysyl-arginine from the c-terminus of pro-hormone pept...
12192079 - Mapping sequence differences between thimet oligopeptidase and neurolysin implicates ke...
8218169 - Identification of substrate-analog trypsin inhibitors through the screening of syntheti...
17174309 - Identification of the ww domain-interaction sites in the unstructured n-terminal domain...
3560229 - Crystallographic refinement and structure of dnase i at 2 a resolution.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-23
Journal Detail:
Title:  Natural product reports     Volume:  -     ISSN:  1460-4752     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8502408     Medline TA:  Nat Prod Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai, 201203, P.R. China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The enhancement of osteogenesis through the use of dental pulp pluripotent stem cells in 3D.
Next Document:  Risk factors for low birth weight in Botucatu city, SP state, Brazil: a study conducted in the publi...