| Tripterygium wilfordii Hook F treatment for idiopathic refractory nephrotic syndrome in adults: a meta-analysis. | |
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MedLine Citation:
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PMID: 19287181 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tripterygium wilfordii Hook F (TwHF) is a Chinese herbal medicine with immunosuppressive effects and an established history of use in the treatment of inflammatory and autoimmune diseases. We have carried out a meta-analysis of randomized controlled trials (RCTs) and quasi-RCTs which assessed the effectiveness of TwHF in the treatment for idiopathic refractory nephrotic syndrome (IRNS). After reading the full text, only three RCTs or quasi-RCTs meeting our inclusion criteria were selected. Our meta-analysis indicated that TwHF has beneficial effects on the remission of IRNS. There was no significant publication bias in the meta-analysis studies. However, studies with a larger sample size and including patients with both a mild and severe histopathological change involvement separately are needed to assess the effects of TwHF in IRNS patients before exact conclusions can be drawn. |
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Authors:
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Gaosi Xu; Weiping Tu; Dongfeng Jiang; Chengyun Xu |
Publication Detail:
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Type: Journal Article; Meta-Analysis; Review Date: 2009-03-14 |
Journal Detail:
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Title: Nephron. Clinical practice Volume: 111 ISSN: 1660-2110 ISO Abbreviation: Nephron Clin Pract Publication Date: 2009 |
Date Detail:
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Created Date: 2009-05-07 Completed Date: 2009-07-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101159763 Medline TA: Nephron Clin Pract Country: Switzerland |
Other Details:
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Languages: eng Pagination: c223-8 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2009 S. Karger AG, Basel. |
Affiliation:
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Department of Nephrology, Second Affiliated Hospital, Nanchang University, No. 1 Minde Road, Nanchang, PR China. xugaosi@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Male Nephrotic Syndrome / drug therapy*, epidemiology* Phytotherapy / methods* Plant Extracts / therapeutic use* Prevalence Treatment Outcome Tripterygium / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Plant Extracts |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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