Document Detail


Triploidy and chromosomes.
MedLine Citation:
PMID:  3966508     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a total sample of 105 triploid spontaneous abortions and live-born and stillborn infants, the parental origin could be determined in 77%. Dispermy was the most common cause of this abnormality. Among the digynic triploids 69% resulted from retention of the second polar body. Parental ages did not differ from those of the general population except for 10 aneuploid triploids with significantly elevated parental ages. In five sibships, simple aneuploidy in another pregnancy was observed, four of them being potentially viable. Two sisters had triploid conceptions. There were four twin pregnancies, a frequency of one in 26. Only two triploids had an XYY sex chromosome complement, one of which was mosaic with loss of an autosome and the other was a chimera. A frequency of almost 50% of mothers exposed to preconception abdominal radiation is suggestive of an association between radiation and triploidy and requires further investigation.
Authors:
I A Uchida; V C Freeman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  151     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-02-11     Completed Date:  1985-02-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  65-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous
Adult
Aneuploidy
Chromosome Aberrations / diagnosis,  etiology,  genetics*
Chromosome Disorders
Culture Techniques
Cytogenetics
Family
Female
Fetus*
Humans
Infant, Newborn
Karyotyping
Male
Pregnancy
Twins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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