| Triplets with feto-fetal transfusion syndrome treated with laser ablation: the USFetus experience. | |
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MedLine Citation:
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PMID: 19658042 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We sought to assess outcomes of triplets with feto-fetal transfusion syndrome (FFTS) treated with selective laser photocoagulation of communicating vessels (SLPCV). STUDY DESIGN: All twins and triplets with FFTS treated with SLPCV were analyzed. Triplets were classified as dichorionic-triamniotic (D/T) or monochorionic-triamniotic (M/T). In M/T triplets, SLPCV between FFTS affected recipient-donor pairs was performed first (step 1); SLPCV of remaining vascular communications was then attempted (step 2). RESULTS: Forty-six of 692 (6.7%) gestations with FFTS treated with SLPCV were triplets; 40 (87%) were D/T, 6 (13%) were M/T. Overall perinatal survivorship in triplets versus twins were not different (73.9% vs. 75.1%, p = 0.757). SLPCV was achieved in 93% of D/T triplets. In the M/T triplets, step 1 was successful in all cases, and step 2 in half of cases. The D/T group delivered later in gestation than the M/T group (31.6 vs. 27.0 weeks, p = 0.049); no difference in overall perinatal survival was detected (75.8% vs. 61.1%, p = 0.248). CONCLUSION: Overall perinatal survival of triplets and twins with FFTS treated via SLPCV is similar. Significant surgical challenges were posed by monochorionic versus dichorionic triplets. Further studies of monochorionic triplets are required to ascertain perinatal survival post-SLPCV in this subset of triplets. |
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Authors:
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Ramen H Chmait; Eftichia Kontopoulos; Patricia W Bornick; Terri Maitino; Rubén A Quintero |
Publication Detail:
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Type: Evaluation Studies; Journal Article; Multicenter Study |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: 23 ISSN: 1476-4954 ISO Abbreviation: J. Matern. Fetal. Neonatal. Med. Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-18 Completed Date: 2010-09-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: England |
Other Details:
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Languages: eng Pagination: 361-5 Citation Subset: IM |
Affiliation:
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Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine, University Southern California, Los Angeles, California 90027, USA. chmait@usc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetal Therapies / methods, statistics & numerical data Fetofetal Transfusion / surgery* Humans Laser Therapy / methods* Pregnancy Pregnancy, Multiple Retrospective Studies Syndrome Treatment Outcome Triplets* Twins United States |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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