Document Detail

Triplets and quadruplets in Switzerland: comparison with singletons, and evolution over the last decade.
MedLine Citation:
PMID:  12825481     Owner:  NLM     Status:  MEDLINE    
AIMS: Main objectives were 1) to determine the incidence of higher multiple births from 1995 to 1998 in Switzerland, and 2) to evaluate neonatal mortality and morbidity. Secondary objectives were 3) to compare the results with those of matched singletons, and 4) to compare the present data to the first Swiss study (1985-1988). METHODS: Retrospective analysis of maternal and neonatal data obtained from all Swiss hospitals. RESULTS: The incidence of triplet births was 1/3247 and that of quadruplet births 1/81,186. The median gestational age was 32 5/7 weeks for triplets, and 28 6/7 weeks for quadruplets. The median birth weight was 1665 g for triplets and 1076 g for quadruplets. Perinatal mortality was 6% for triplets and 19% for quadruplets. Respiratory distress syndrome was the major morbidity as diagnosed in 52% of triplets and 81% of quadruplets. A comparison of triplets with matched singletons showed no significant differences in morbidity and mortality. Compared with the first Swiss study, the mortality rate decreased, while the incidence of triplets increased but decreased for quadruplets. CONCLUSION: The incidence of higher-order multiple births in Switzerland dropped for quadruplets in the last decade but has increased for triplets. The mortality and morbidity of triplets is comparable to that of singletons with a similar gestational age.
Romaine Arlettaz; Elena Paraskevopoulos; Hans-Ulrich Bucher
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  31     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2003  
Date Detail:
Created Date:  2003-06-26     Completed Date:  2003-10-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  242-50     Citation Subset:  IM    
Neonatal Unit, University Hospital, Zurich, Switzerland.
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MeSH Terms
Cesarean Section
Fertilization in Vitro
Gestational Age
Infant Mortality
Infant, Newborn
Ovulation Induction
Pregnancy, Multiple / statistics & numerical data*
Respiratory Distress Syndrome, Newborn / epidemiology
Sperm Injections, Intracytoplasmic

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