Document Detail

Triplets: outcomes of expectant management versus multifetal reduction for 127 pregnancies.
MedLine Citation:
PMID:  10942486     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Our purpose was to compare outcomes of women with triplet gestations conceived via assisted reproductive technology who chose expectant management or multifetal pregnancy reduction. STUDY DESIGN: We performed a retrospective review of all women who initiated assisted reproductive technology cycles from August 1995 through July 1997 with ultrasonographic documentation of triplets exhibiting fetal heart tones at 9 weeks of gestation (N = 127). Patients were then uniformly referred to a maternal-fetal medicine specialist and to 3 centers offering multifetal pregnancy reduction. RESULTS: Thirty-six percent of patients (46/127) chose multifetal pregnancy reduction with 95% undergoing reduction to twins. In the expectant management group, 13.6% of pregnancies were reduced spontaneously after 9 weeks of gestation. The "take home" infant per delivery rates for the multifetal pregnancy reduction and expectant management groups were 87% and 90.1%, respectively (P =.66). The mean gestational ages at delivery (+/-SE) for the multifetal pregnancy reduction and expectant management groups were 33.25 +/- 1. 03 weeks and 32.04 +/- 0.58 weeks (P =.23), and the mean birth weights of infants delivered at >24 weeks of gestation were 2226 +/- 79 and 1796 +/- 44, respectively (P <.0001). There were no significant differences in perinatal mortality, gestational age at delivery, or "take home" infant per delivery rates between these groups. CONCLUSIONS: These data suggest that multifetal pregnancy reduction does not have a significant impact on the probability of live birth or on gestational age at delivery for women with triplets conceived with assisted reproductive technology.
M P Leondires; S D Ernst; B T Miller; R T Scott
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  183     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-09-21     Completed Date:  2000-09-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  454-9     Citation Subset:  AIM; IM    
Saint Barnabas Medical Center, Livingston, NJ, USA.
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MeSH Terms
Abortion, Spontaneous
Delivery, Obstetric
Gestational Age
Infant Mortality
Infant, Newborn
Pregnancy Outcome*
Pregnancy Reduction, Multifetal*
Pregnancy, Multiple*
Comment In:
Am J Obstet Gynecol. 2001 Apr;184(5):1040-1; author reply 1042-3   [PMID:  11303220 ]
Am J Obstet Gynecol. 2001 Apr;184(5):1041-3   [PMID:  11303221 ]

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