Document Detail


Triple-site pacing: a new supported therapy approach for bridge to recovery with a left ventricular assist system in a patient with idiopathic dilated cardiomyopathy.
MedLine Citation:
PMID:  20174955     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Left ventricular assist devices (LVAD) are widely used as bridges to cardiac transplantation or for destination therapy. LVAD support may also function as a bridge to ventricular recovery, but a sufficient rate of recovery has not been obtained, even with various adjuvant therapies. Cardiac resynchronization therapy (CRT) is an effective treatment for heart failure, and there is a report of successful weaning off LVAD with CRT. However, some patients with CRT could not improve their cardiac function because of residual dyssynchrony. Herein, we describe a case of a successful bridge to recovery with triple-site pacing for residual dyssynchrony after biventricular pacing. A 34-year-old woman with heart failure due to dilated cardiomyopathy whose condition deteriorated underwent Toyobo LVAD implantation, resulting in improvement of the left ventricular ejection fraction (LVEF) from 12 to 36%. Because of left ventricular dyssynchrony, we performed CRT, but residual dyssynchrony impeded cardiac recovery. We inserted an additional ventricular lead at the right ventricular outlet to achieve triple-site pacing in order to obtain complete synchronization. The LVEF improved to 45%, and the patient was successfully weaned off the LVAD. In LVAD-supported cases of persistent left ventricular dyssynchrony with CRT, implantation of triple-site pacing could potentially accelerate recovery.
Authors:
Takashi Nishimura; Shunei Kyo
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-02-20
Journal Detail:
Title:  Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs     Volume:  13     ISSN:  1619-0904     ISO Abbreviation:  J Artif Organs     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-05     Completed Date:  2010-06-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815648     Medline TA:  J Artif Organs     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  54-7     Citation Subset:  IM    
Affiliation:
Division of Therapeutic Strategy for Heart Failure, Department of Cardiothoracic Surgery, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan. takashin-tky@umin.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Cardiac Pacing, Artificial*
Cardiomyopathy, Dilated / complications,  surgery*,  ultrasonography
Female
Heart Failure / etiology,  surgery,  ultrasonography
Heart-Assist Devices*
Humans
Stroke Volume / physiology
Treatment Outcome
Ventricular Dysfunction, Left / surgery,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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