Document Detail


Trinucleotide repetition and fragile X syndrome.
MedLine Citation:
PMID:  9109809     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Insufficiently appreciated as a cause of learning disability and other behavioral problems, fragile X syndrome accounts for almost 10% of inherited mental retardation. Identification of the specific mutation as a dramatic trinucleotide expansion inaugurates an era of accurate diagnosis, and goes far toward explaining the syndrome's inheritance patterns, in which risk varies as the disease descends through a family.
Authors:
S T Warren
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Hospital practice (1995)     Volume:  32     ISSN:  2154-8331     ISO Abbreviation:  Hosp Pract (Minneap)     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-05-08     Completed Date:  1997-05-08     Revised Date:  2010-06-18    
Medline Journal Info:
Nlm Unique ID:  101268948     Medline TA:  Hosp Pract (Minneap)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  73-6, 81-5, 90-2 passim     Citation Subset:  AIM; IM    
Affiliation:
Emory University School of Medicine, Atlanta, USA.
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Female
Fragile X Syndrome / genetics*
Genotype
Humans
Male
Molecular Biology
Pedigree
Phenotype
Sex Factors
Trinucleotide Repeats / genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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