| Trimethoprim-sulfamethoxazole therapy for infective endocarditis. | |
| | |
MedLine Citation:
|
PMID: 7029718 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A man with stenosis of the aortic valve acquired endocarditis after abdominal surgery. Klebsiella pneumoniae and Acinetobacter calcoaceticus were cultured from his blood. The blood cultures remained positive despite intravenous gentamicin and cephalothin to which the organisms were sensitive in vitro. Ultimately, the blood was sterilized by a combination of gentamicin and trimethoprim-sulfamethoxazole taken orally. The course of the patient was complicated by cardiac arrest and pericardial tamponade caused by a valve ring abscess and a dissecting mycotic aneurysm of the coronary sinus of Valsalva. Aortic valve replacement and right coronary artery bypass were performed. A prolonged course of trimethoprim-sulfamethoxazole was given postoperatively, and the patient has had no evidence of recurrent infection after five years. Trimethoprim-sulfamethoxazole, in combination with other antibiotics, has been successfully used to treat other patients with bacterial endocarditis and thus may be an alternative for patients in whom conventional therapy has failed. |
| | |
Authors:
|
R C Noble; R M Cooper; A L Jarvis; P L Caples; E P Todd |
Related Documents
:
|
12464818 - Fatal salmonella aortitis with mycotic aneurysm rupture. 12659998 - Sinus of valsalva aneurysm as a cause of right proximal coronary artery spasm. 19458178 - Mycotic aortic aneurysm associated with legionella anisa. 20331488 - Repair of aorto-left ventricular tunnel arising from the left sinus of valsalva. 15246308 - Adverse central nervous system sequelae after selective transforaminal block: the role ... 1975688 - Right atrial myxoma with a nonembolic intestinal manifestation. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Southern medical journal Volume: 74 ISSN: 0038-4348 ISO Abbreviation: South. Med. J. Publication Date: 1981 Nov |
Date Detail:
|
Created Date: 1982-01-09 Completed Date: 1982-01-09 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0404522 Medline TA: South Med J Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1299-303 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acinetobacter Infections
/
drug therapy Aneurysm, Infected / surgery Drug Combinations Endocarditis, Bacterial / drug therapy* Humans Klebsiella Infections / drug therapy Klebsiella pneumoniae Male Middle Aged Sulfamethoxazole / therapeutic use* Trimethoprim / therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
0/Drug Combinations; 723-46-6/Sulfamethoxazole; 738-70-5/Trimethoprim |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Monitoring of serum theophylline concentrations.
Next Document: Differential diagnosis of acute weakness.