Document Detail


Trimethoprim-sulfamethoxazole-induced Stevens-Johnson syndrome: a case report.
MedLine Citation:
PMID:  20660883     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Stevens-Johnson syndrome and toxic epidermal necrolysis are rare; however, when they occur, they usually present with severe reactions in response to medications and other stimuli. These reactions are characterized by mucocutaneous lesions, which ultimately lead to epidermal death and sloughing. We present a unique case report of Stevens-Johnson syndrome and associated toxic epidermal necrolysis in a 61-year-old man after treatment for a peripherally inserted central catheter infection with trimethoprim-sulfamethoxazole. This case report reviews a rare adverse reaction to a commonly prescribed antibiotic drug used in podiatric medical practice for the management of diabetic foot infections.
Authors:
Michael R Langlois; Francis Derk; Ronald Belczyk; Thomas Zgonis
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Podiatric Medical Association     Volume:  100     ISSN:  1930-8264     ISO Abbreviation:  J Am Podiatr Med Assoc     Publication Date:    2010 Jul-Aug
Date Detail:
Created Date:  2010-07-27     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501423     Medline TA:  J Am Podiatr Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  299-303     Citation Subset:  IM    
Affiliation:
Orthopaedics/Division of Podiatric Medicine and Surgery, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
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MeSH Terms
Descriptor/Qualifier:
Anti-Infective Agents / administration & dosage,  adverse effects*
Diabetic Foot / drug therapy
Epidermal Necrolysis, Toxic / etiology
Humans
Male
Middle Aged
Osteomyelitis / drug therapy,  surgery
Stevens-Johnson Syndrome / chemically induced*
Trimethoprim-Sulfamethoxazole Combination / administration & dosage,  adverse effects*
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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