Document Detail

Triiodothyronine (T3) concentration and therapy in autistic children.
MedLine Citation:
PMID:  215586     Owner:  NLM     Status:  MEDLINE    
The clinical and biochemical status of thyroid function of patients with an autistic syndrome was investigated. The study consisted of 13 patients between the ages of 7 and 21 years. There was no clinical evidence for hypothyroidism in any patient, and T3, T4, and TSH concentrations were within the normal range. Two patients who had retarded bone ages were treated with triiodothyronine for 6 months. Hyperthyroidism developed when T3 levels exceeded physiologic concentrations in these patients. The concept that the clinical response to triiodothyronine in autistic patients results from correction of thyroid dysfunction is not supported by these findings.
V Abbassi; T Linscheid; M Coleman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of autism and childhood schizophrenia     Volume:  8     ISSN:  0021-9185     ISO Abbreviation:  J Autism Child Schizophr     Publication Date:  1978 Dec 
Date Detail:
Created Date:  1979-03-24     Completed Date:  1979-03-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1264240     Medline TA:  J Autism Child Schizophr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  383-7     Citation Subset:  IM    
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MeSH Terms
Age Determination by Skeleton
Autistic Disorder / drug therapy*,  physiopathology
Hyperthyroidism / chemically induced
Thyroid Gland / physiopathology
Thyrotropin / blood
Thyroxine / blood
Triiodothyronine / adverse effects,  blood*,  therapeutic use
Reg. No./Substance:
6893-02-3/Triiodothyronine; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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