| Trigonella foenum graecum (fenugreek) seed extract as an antineoplastic agent. | |
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MedLine Citation:
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PMID: 11351364 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The antineoplastic effect of Trigonella foenum graecum seed extract has been evaluated in the Ehrlich ascites carcinoma (EAC) model in Balb-C mice. Intra-peritoneal administration of the alcohol extract of the seed both before and after inoculation of EAC cell in mice produced more than 70% inhibition of tumour cell growth with respect to the control. Treatment with the extract was found to enhance both the peritoneal exudate cell and macrophage cell counts. The extract also produced a significant antiinflammatory effect. We report here the antiinflammatory and antineoplastic effects, of Trigonella foenum graecum seed extract. |
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Authors:
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P Sur; M Das; A Gomes; J R Vedasiromoni; N P Sahu; S Banerjee; R M Sharma; D K Ganguly |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Phytotherapy research : PTR Volume: 15 ISSN: 0951-418X ISO Abbreviation: Phytother Res Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-05-14 Completed Date: 2001-08-23 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: England |
Other Details:
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Languages: eng Pagination: 257-9 Citation Subset: IM |
Copyright Information:
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Copyright 2001 John Wiley & Sons, Ltd. |
Affiliation:
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Division of Pharmacology and Experimental Therapeutics, Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Calcutta - 700 032, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anti-Inflammatory Agents / pharmacology*, therapeutic use Antineoplastic Agents / pharmacology*, therapeutic use Carcinoma, Ehrlich Tumor / chemically induced, prevention & control* Carrageenan Edema / chemically induced, prevention & control* Mice Mice, Inbred BALB C Plant Extracts* / pharmacology, therapeutic use Plants, Medicinal* Rats Rats, Sprague-Dawley Seeds Trigonella |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Antineoplastic Agents; 0/Plant Extracts; 68990-15-8/fenugreek seed meal; 9000-07-1/Carrageenan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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