| Triglyceride-rich lipoproteins and plasma lipid transport. | |
| | |
MedLine Citation:
|
PMID: 20018941 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This memoir provides a history of the triglyceride-rich lipoproteins of blood plasma over the last half-century. As precursors of low-density lipoproteins and in their own right, triglyceride-rich lipoproteins are essential to the formation of atherosclerotic plaques and to consequent ischemic vascular disease. The author recounts research at the National Heart Institute during 1953 to 1956 and continuing thereafter at the University of California San Francisco. Emphasis is placed on key insights arising from investigations of human disease, the interplay of fatty acid and triglyceride-transport involving the liver, small intestine, adipose tissue and muscle, and the role of the liver in the synthesis and catabolism of atherogenic lipoproteins. |
| | |
Authors:
|
Richard J Havel |
Publication Detail:
|
Type: Historical Article; Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Arteriosclerosis, thrombosis, and vascular biology Volume: 30 ISSN: 1524-4636 ISO Abbreviation: Arterioscler. Thromb. Vasc. Biol. Publication Date: 2010 Jan |
Date Detail:
|
Created Date: 2009-12-18 Completed Date: 2010-01-14 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9505803 Medline TA: Arterioscler Thromb Vasc Biol Country: United States |
Other Details:
|
Languages: eng Pagination: 9-19 Citation Subset: IM |
Affiliation:
|
Professor Emeritus, Cardiovascular Research Institute, UCSF, 513 Parnassus Ave, San Francisco, CA 94143-0130, USA. richard.havel@ucsf.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Biomedical Research / history* Cardiovascular Diseases / history* History, 20th Century Humans Lipoproteins / history* San Francisco Triglycerides / history* |
| Chemical | |
Reg. No./Substance:
|
0/Lipoproteins; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Lipolysis needed for chylomicron uptake?
Next Document: Glyco-conjugates as elicitors or suppressors of plant innate immunity.