Document Detail


Triggering for submaximal exercise level in gastric exercise tonometry: serial lactate, heart rate, or respiratory quotient?
MedLine Citation:
PMID:  17385029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gastric exercise tonometry is a functional diagnostic test in chronic gastrointestinal ischemia. As maximal exercise can cause false-positive tests, exercise buildup should be controlled to remain submaximal. We evaluated three parameters for monitoring and adjusting exercise levels (heart rate [HR], respiratory quotient [RQ], and serial lactate measurements) in 178 tests in both healthy volunteers and patients suspected of gastrointestinal ischemia. Exercise levels above submaximal occurred in 20% of HR-, 2% of RQ-, and 5% of lactate-monitored tests (P<0.05 for HR vs. RQ and lactate). Low levels were seen in 5% of HR-, 10% of RQ-, and 41% of lactate-monitored tests (P<0.01 for lactate vs. HR and RQ). High levels resulted in 43% false-positive tonometry results compared to 19% of all tests (P<0.001); low levels did not result in more false negatives (5% vs. 6%). Although RQ monitoring yielded the greatest proportion of optimal exercise tests, serial lactate monitoring is our method of choice, combining optimal diagnostic accuracy, low cost, and simplicity.
Authors:
Johannes A Otte; Ellie Oostveen; Peter B F Mensink; Robert H Geelkerken; Jeroen J Kolkman
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Publication Detail:
Type:  Journal Article     Date:  2007-03-24
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  52     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-06-28     Completed Date:  2007-08-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1771-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Internal Medicine, Medisch Spectrum Twente, Enschede, The Netherlands. jaotte@zeelandnet.nl
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Bicarbonates / blood
Environmental Monitoring / methods
Exercise Test*
Female
Heart Rate*
Humans
Ischemia
Lactates / blood*
Male
Manometry*
Middle Aged
Respiratory Physiological Phenomena*
Stomach / blood supply*
Chemical
Reg. No./Substance:
0/Bicarbonates; 0/Lactates
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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