Document Detail

Trigeminal trophic syndrome.
MedLine Citation:
PMID:  17269524     Owner:  NLM     Status:  MEDLINE    
Ulceration of the nose may be inadvertently induced by the patient. Although trigeminal trophic syndrome is an uncommon cause of chronic ulcers, healthcare providers should consider the possibility of this disorder when encountering a patient with nasal ulcerations. Trigeminal trophic syndrome most commonly occurs in older women following therapy for trigeminal neuralgia. The ulcers usually involve the nasal ala and paranasal areas. The clinical vignette of a man with a self-induced nasal ulcer secondary to trigeminal trophic syndrome, which was initially suspected to be skin cancer, is presented. Since nasal ulcerations can be secondary to other conditions, a lesional biopsy should be performed to exclude other diagnoses when trigeminal trophic syndrome is entertained. In addition to trigeminal trophic syndrome, the differential diagnosis of conditions that can cause nasal ulcers include factitial disorders with self-induced ulcerations (such as dermatitis artifacta and neurotic excoriations), granulomatous conditions, infectious diseases, malignancy, and pyoderma gangrenosum. Treatment of trigeminal trophic syndrome requires prevention of digital manipulation of the lesion-either by occluding contact with the ulcer, initiating psychotropic medication, or both. Psychiatric and/or pharmacologic intervention should be considered to reduce or resolve further habitual self-inflicted injury before surgical intervention.
Hedy G Setyadi; Philip R Cohen; Keith E Schulze; Stephen H Mason; Paul T Martinelli; Eugene L Alford; George E Taffet; Bruce R Nelson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  100     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-02-02     Completed Date:  2007-02-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  43-8     Citation Subset:  AIM; IM    
Baylor College of Medicine, USA.
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MeSH Terms
Aged, 80 and over
Antipsychotic Agents / therapeutic use*
Behavior Control / methods*
Dementia / complications,  drug therapy
Diagnosis, Differential
Trigeminal Nerve Diseases / complications,  diagnosis*,  therapy*
Vitamin B Complex / therapeutic use*
Reg. No./Substance:
0/Antipsychotic Agents; 12001-76-2/Vitamin B Complex
Comment In:
South Med J. 2007 Jan;100(1):3   [PMID:  17269515 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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