| Trigeminal projections on gustatory neurons of the nucleus of the solitary tract: a double-label strategy using electrical stimulation of the chorda tympani and tracer injection in the lingual nerve. | |
| | |
MedLine Citation:
|
PMID: 19595675 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Taste and sensory information are closely associated and our electrophysiological studies showed a trigeminal modulation of gustatory neurons in the nucleus of the solitary tract (NST). Chorda tympani (CT) and lingual nerves (LN) converge centrally in the rostral subdivision of the NST in hamsters and rats. However, no study has yet revealed the details of this overlap on a same section. We therefore used a double-label strategy to visualize neurons in the NST that receive both trigeminal and gustatory inputs. An anterograde tracer (BDA, Biotinylated Dextran Amine) was applied unilaterally to the cut central end of the LN in male Sprague-Dawley rats. One week later, the ipsilateral CT was electrically stimulated, after which animals were perfused and brainstem sections double-labelled for Fos immunoreactivity of activated NST neurons and BDA labelling of LN afferents. Our results permitted to circumscribe the regional overlap of the trigeminal and CT afferents mainly in the rostral central (RC) subdivision of the gustatory NST. Fos-immunoreactive neurons were observed to be closely apposed by BDA-labelled fibres and terminal boutons. Such varicosities mainly "en passant" were especially present in the RC zone of the nucleus. These observations provide an anatomical substrate for trigemino-gustatory interactions. |
| | |
Authors:
|
Rufino Felizardo; Yves Boucher; Adeline Braud; Earl Carstens; Céline Dauvergne; Fawzia Zerari-Mailly |
Related Documents
:
|
9482235 - Organization of direct hippocampal efferent projections to the cerebral cortex of the r... 2468515 - Fluorometric comparisons of the retrograde axonal transport of true blue and diamidino ... 18262505 - Collateral projections from the subfornical organ to the median preoptic nucleus and pa... 9483515 - The ventrolateral periaqueductal gray projects to caudal brainstem depressor regions: a... 6234055 - Characteristic alterations in responses to imposed wrist displacements in parkinsonian ... 16137985 - Regional dendritic variation in neonatal human cortex: a quantitative golgi study. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-07-10 |
Journal Detail:
|
Title: Brain research Volume: 1288 ISSN: 1872-6240 ISO Abbreviation: Brain Res. Publication Date: 2009 Sep |
Date Detail:
|
Created Date: 2009-08-31 Completed Date: 2009-10-15 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0045503 Medline TA: Brain Res Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 60-8 Citation Subset: IM |
Affiliation:
|
UFR d'Odontologie, APHP Université Denis Diderot P7- CRICM UMRS 975- Paris, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Chorda Tympani Nerve / anatomy & histology, physiology* Electric Stimulation Immunohistochemistry Lingual Nerve / anatomy & histology, physiology* Male Neurons, Afferent / physiology* Proto-Oncogene Proteins c-fos / metabolism Rats Solitary Nucleus / anatomy & histology, metabolism, physiology* Staining and Labeling Trigeminal Nerve / anatomy & histology, physiology* |
| Chemical | |
Reg. No./Substance:
|
0/Proto-Oncogene Proteins c-fos |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Decreased cell proliferation in the dentate gyrus does not associate with development of anhedonic-l...
Next Document: Cellular mechanisms underlying affective resiliency: the role of glucocorticoid receptor- and mitoch...