Document Detail


Trigeminal and polyradiculoneuritis in a dog presenting with masticatory muscle atrophy and Horner's syndrome.
MedLine Citation:
PMID:  12102209     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 9-year-old, spayed female, Airedale Terrier was euthanatized and necropsied after a progressive clinical course that included Horner's syndrome of the left eye and unilateral atrophy of the masticatory muscles. Although gross lesions were limited, a polyradiculoneuritis and ganglionitis that was most severe in the trigeminal nerves and ganglia were confirmed histologically. The inflammatory infiltrate consisted predominantly of macrophages and B and T lymphocytes that were phenotypically confirmed by immunostaining. Horner's syndrome was the result of damage to postganglionic sympathetic fibers that were incorporated in segments of the inflamed trigeminal nerve and its ophthalmic branch. Histologically, the character and distribution of the inflammation was similar to previously described syndromes of suspected immune-mediated etiology in humans and animals.
Authors:
R J Panciera; J W Ritchey; J E Baker; M DiGregorio
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Veterinary pathology     Volume:  39     ISSN:  0300-9858     ISO Abbreviation:  Vet. Pathol.     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-07-09     Completed Date:  2002-12-20     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0312020     Medline TA:  Vet Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  146-9     Citation Subset:  IM    
Affiliation:
College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA. rpancie@okstate.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Atrophy
Diagnosis, Differential
Dog Diseases / pathology*
Dogs
Euthanasia
Horner Syndrome / pathology,  veterinary*
Mandibular Nerve / pathology
Masticatory Muscles / pathology*
Polyradiculoneuropathy / pathology,  veterinary*
Trigeminal Ganglion / pathology
Trigeminal Nerve Diseases / pathology,  veterinary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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