Document Detail

Trigeminal nerve injuries in relation to the local anaesthesia in mandibular injections.
MedLine Citation:
PMID:  21072069     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: This study reports the signs and symptoms that are the features of trigeminal nerve injuries caused by local anaesthesia (LA).
METHODS: Thirty-three patients with nerve injury following LA were assessed. All data were analysed using the SPSS statistical programme and Microsoft Excel.
RESULTS: Lingual nerve injury (LNI; n = 16) and inferior alveolar nerve injury (IANI; n = 17) patients were studied. LNI were more likely to be permanent. Neuropathy was demonstrable in all patients with varying degrees of paraesthesia, dysaesthesia (in the form of burning pain) allodynia and hyperalgesia. All injuries were unilateral. A significantly greater proportion of LNI patients (75%) had received multiple injections, in comparison to IANI patients (41%) (p <0.05). Fifty percent of patients with LNI reported pain on injection. The presenting signs and symptoms of both LNI and IANI included pain. These symptoms of neuropathy were constant in 88% of the IANI group and in 44% of LNI patients. Functional difficulties were different between the LNI and IANI groups, a key difference being the presence of severely altered taste perception in nine patients with LA-induced LNI.
CONCLUSIONS: Chronic pain is often a symptom after local anaesthetic-induced nerve injury. Patients in the study population with lingual nerve injury were significantly more likely to have received multiple injections compared to those with IANI.
T Renton; D Adey-Viscuso; J G Meechan; Z Yilmaz
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  British dental journal     Volume:  209     ISSN:  1476-5373     ISO Abbreviation:  Br Dent J     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-12     Completed Date:  2011-03-25     Revised Date:  2011-05-23    
Medline Journal Info:
Nlm Unique ID:  7513219     Medline TA:  Br Dent J     Country:  England    
Other Details:
Languages:  eng     Pagination:  E15     Citation Subset:  D; IM    
Oral Surgery Department, King's College London Dental Institute, UK.
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MeSH Terms
Anesthesia, Local / adverse effects*
Anesthetics, Local / administration & dosage*,  adverse effects
Chin / innervation
Cranial Nerve Injuries / etiology
Gingiva / innervation
Hyperalgesia / etiology
Hypesthesia / etiology
Iatrogenic Disease
Injections / adverse effects,  statistics & numerical data
Lidocaine / administration & dosage,  adverse effects
Lingual Nerve / injuries
Lip / innervation
Mandibular Nerve / injuries
Middle Aged
Pain / etiology
Paresthesia / etiology
Prilocaine / administration & dosage,  adverse effects
Sex Factors
Speech Disorders / etiology
Taste Disorders / etiology
Tongue / innervation
Tooth / innervation
Trigeminal Nerve / injuries*
Trigeminal Neuralgia / etiology
Reg. No./Substance:
0/Anesthetics, Local; 137-58-6/Lidocaine; 721-50-6/Prilocaine
Comment In:
Br Dent J. 2010 Nov;209(9):452-3   [PMID:  21072098 ]
Br Dent J. 2011 Apr 9;210(7):293   [PMID:  21475262 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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