| Tricuspid valve disease with significant tricuspid insufficiency in the fetus: diagnosis and outcome. | |
| | |
MedLine Citation:
|
PMID: 1987222 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The echocardiographic studies and clinical course of 27 fetuses (mean gestational age 26.9 weeks) diagnosed in utero with tricuspid valve disease and significant tricuspid regurgitation were reviewed. The diagnosis of Ebstein's anomaly was made in 17 of the fetuses, 7 had tricuspid valve dysplasia with poorly developed but normally attached leaflets and 2 had an unguarded tricuspid valve orifice with little or no identifiable tricuspid tissue. One fetus was excluded from data analysis because a more complex heart lesion was documented at autopsy. All fetuses had massive right atrial dilation and most who were serially studied had progressive right-sided cardiomegaly. Hydrops fetalis was found in six cases and atrial flutter in five. Associated cardiac lesions included pulmonary stenosis in five cases and pulmonary atresia in six. Four fetuses with normal forward pulmonary artery flow at the initial examination were found at subsequent study to have retrograde pulmonary artery and ductal flow in association with the development of pulmonary stenosis (n = 1) and pulmonary atresia (n = 3). On review of the clinical course of the 23 fetuses (excluding 3 with elective abortion), 48% of the fetuses died in utero and 35% who were liveborn died despite vigorous medical and, when necessary, surgical management, many of whom had severe congestive heart failure. Of the four infants who survived the neonatal period, three had a benign neonatal course, all of whom were diagnosed with mild to moderate Ebstein's anomaly; only one had pulmonary outflow obstruction. An additional finding at autopsy was significant lung hypoplasia documented in 10 of 19 autopsy reports.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
L K Hornberger; D J Sahn; C S Kleinman; J A Copel; K L Reed |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of the American College of Cardiology Volume: 17 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 1991 Jan |
Date Detail:
|
Created Date: 1991-02-21 Completed Date: 1991-02-21 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 167-73 Citation Subset: AIM; IM |
Affiliation:
|
Department of Pediatrics, Division University of California-San Diego Medical Center, California. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Ebstein Anomaly
/
mortality,
ultrasonography* Echocardiography* Female Fetal Diseases / mortality, ultrasonography* Fetal Heart / ultrasonography* Humans Pregnancy Retrospective Studies Tricuspid Valve / abnormalities* Tricuspid Valve Insufficiency / mortality, ultrasonography* Ultrasonography, Prenatal* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Longitudinal dissociation of atrioventricular accessory pathways.
Next Document: Electrophysiologic findings after Fontan repair of functional single ventricle.