| Tricuspid annular plane systolic excursion and right ventricular ejection fraction in pediatric and adolescent patients with tetralogy of Fallot, patients with atrial septal defect, and age-matched normal subjects. | |
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MedLine Citation:
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PMID: 20835905 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To determine whether TAPSE is an accurate marker of right ventricular (RV) systolic function in patients with tetralogy of Fallot (TOF) and patients with small atrial septal defect (ASD). The tricuspid annular plane systolic excursion (TAPSE) values were measured and compared with RV ejection fraction (EF). METHODS AND RESULTS: A prospective study was conducted in pediatric and adolescent patients with TOF (n = 110), with isolated small secundum ASD (n = 200), and age-matched patients with normally structured heart. The TAPSE values showed a positive correlation with age in both patients with ASD and normal subjects. No significant difference of TAPSE values was seen in control subjects and age-matched ASD patients. The TAPSE was not decreased compared to normal subjects in eight infant TOF patients before corrective surgery. A reduction of TAPSE values with increasing time interval following corrective surgery was seen. After a mean of 7 years TAPSE values become significantly reduced compared to age-matched controls, being below the lower bound of the -2 SD. CONCLUSION: In ASD patients the systolic RV function was preserved over the pediatric age group when compared to normal subjects. In contrast, although initially preserved, we found an impaired TAPSE with increasing postoperative period in our TOF patients. |
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Authors:
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Martin Koestenberger; Bert Nagel; William Ravekes; Allen D Everett; Hans Peter Stueger; Bernd Heinzl; Erich Sorantin; Gerhard Cvirn; Andreas Gamillscheg |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article Date: 2010-09-12 |
Journal Detail:
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Title: Clinical research in cardiology : official journal of the German Cardiac Society Volume: 100 ISSN: 1861-0692 ISO Abbreviation: Clin Res Cardiol Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-18 Completed Date: 2011-05-16 Revised Date: 2011-12-15 |
Medline Journal Info:
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Nlm Unique ID: 101264123 Medline TA: Clin Res Cardiol Country: Germany |
Other Details:
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Languages: eng Pagination: 67-75 Citation Subset: IM |
Affiliation:
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Division of Pediatric Cardiology, Department of Pediatrics, Medical University Graz, Auenbruggerplatz 30, 8036, Graz, Austria. Martin.Koestenberger@medunigraz.at |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Child, Preschool Echocardiography / methods* Female Heart Septal Defects, Atrial / complications, diagnosis* Humans Image Interpretation, Computer-Assisted / methods Infant Infant, Newborn Magnetic Resonance Imaging Male Reproducibility of Results Sensitivity and Specificity Stroke Volume* Systole Tetralogy of Fallot / complications, diagnosis* Tricuspid Valve / ultrasonography* Ventricular Dysfunction, Right / diagnosis*, etiology Young Adult |
| Comments/Corrections | |
Comment In:
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Clin Res Cardiol. 2011 Aug;100(8):711
[PMID:
21409594
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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