Document Detail


Tricuspid Valve Mycetoma in an Infant Successfully Treated by Excision and Complex Tricuspid Valve Repair Followed by Fluconazole Therapy.
MedLine Citation:
PMID:  24116856     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Background: Fungal valve endocarditis in children is an uncommon and lethal disease. The risk increases with use of central venous catheters (CVC), total parenteral nutrition (TPN), and use of broad-spectrum antibiotics during the neonatal period. Due to high mortality, a combination of surgery and antifungal therapy is usually recommended for treatment. Methods: Case report and review of the literature. Results: We present a case of an asymptomatic infant with multiple Candida tricuspid valve mycetomas. Complete cure was achieved by combined tricuspid valve repair and fluconazole therapy. We also review 26 cases of tricuspid valve Candida endocarditis in children published in the literature. Conclusion: From being uniformly fatal five decades ago to a current survival rate of 64% to 100%, the prognosis of Candida endocarditis has changed dramatically with the use of antifungal therapy alone or in combination with surgery. Our case re-emphasizes the role of valve-sparing debridement with repair of the native valve using autologous pericardium in combination with long-term antifungal therapy as a feasible option in managing tricuspid valve Candida endocarditis.
Authors:
V Anil Kumar; Edwin Francis; Sreekala Sreehari; Benedict Raj
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-10-12
Journal Detail:
Title:  Surgical infections     Volume:  -     ISSN:  1557-8674     ISO Abbreviation:  Surg Infect (Larchmt)     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-10-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815642     Medline TA:  Surg Infect (Larchmt)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1 Department of Microbiology, Amrita Institute of Medical Sciences , Kerala, India .
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