Document Detail


Tricuspid Annular Peak Systolic Velocity (S') in Children and Young Adults with Pulmonary Artery Hypertension Secondary to Congenital Heart Diseases, and in Those with Repaired Tetralogy of Fallot: Echocardiography and MRI Data.
MedLine Citation:
PMID:  22763086     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Tricuspid annular peak systolic velocity (S'), as an echocardiographic index to assess right ventricular (RV) systolic function, has not been investigated thoroughly in children and young adults with repaired tetralogy of Fallot (TOF) and pulmonary artery hypertension secondary to congenital heart disease (PAH-CHD). METHODS: S' values in patients with TOF (n = 183) and PAH-CHD (n = 55) were compared with those in normal subjects. S' values were compared with RV ejection fraction and RV end-diastolic volume index (RVEDVi) determined by magnetic resonance imaging. RESULTS: S' values became significantly reduced in PAH-CHD patients after 10.4 years of age and after 13.6 years of age in patients with TOF compared with the lower boundary of the ±2-SD interval of normal subjects. Significant positive correlations between S' and RV ejection fraction were seen in patients with TOF (r = 0.66, P < .001) and those with PAH-CHD (r = 0.82, P < .001). Significant negative correlations between S' and RVEDVi were also seen in patients with repaired TOF (r = -0.29, P = .002) and in those with PAH-CHD (r = -0.59, P < .001). CONCLUSIONS: Although initially preserved, in this prospective study, impaired S' values with increasing age were found in patients with repaired TOF and PAH-CHD. Persistent pressure overload in patients with PAH-CHD as well as volume overload in those with repaired TOF might lead to systolic RV functional impairment and increased RVEDVi. The validity of S' data was supported by magnetic resonance imaging data (RVEDVi and RV ejection fraction).
Authors:
Martin Koestenberger; Bert Nagel; William Ravekes; Alexander Avian; Bernd Heinzl; Andrea Fandl; Thomas Rehak; Erich Sorantin; Gerhard Cvirn; Andreas Gamillscheg
Related Documents :
21955866 - Outcome of peritoneal dialysis in cirrhotic patients with end-stage renal disease - a 2...
22744736 - A clinicopathological study of serotonin of sigmoid colon mucosa in association with ch...
20357496 - Alterations of lipid metabolism in chronic nephropathies: mechanisms, diagnosis and tre...
22582496 - Interaction between selenium and arsenic in biological samples of psoriasis patients.
3435566 - Undiagnosed chronic monarthritis. clinical and evolutionary profile.
24895326 - The microrna-200 family-a potential diagnostic marker in hepatocellular carcinoma?
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-3
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  -     ISSN:  1097-6795     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved.
Affiliation:
Division of Pediatric Cardiology, Department of Pediatrics, Medical University Graz, Graz, Austria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Index-Beat Assessment of Left Ventricular Systolic and Diastolic Function during Atrial Fibrillation...
Next Document:  Effects of cardiorespiratory fitness on aging: glucose trajectory in a cohort of healthy men.