Document Detail


Triclosan in waste and surface waters from the upper Detroit River by liquid chromatography-electrospray-tandem quadrupole mass spectrometry.
MedLine Citation:
PMID:  15910958     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) is an antimicroibial disinfectant agent used in a wide array of consumer products. An analytical method based on solid-phase extraction (SPE) followed by reverse phase, liquid chromatography coupled with electrospray ionization (negative)-tandem quadrupole mass spectrometry (LC-ESI(-)-MS/MS; in the multiple reaction monitoring (MRM) mode) was developed, optimized and validated for the determination of triclosan in wastewater/sewage treatment plant (WSTP) effluent and surface waters from the upper Detroit River (Canada). The mean recoveries (+/-%RSD) of triclosan and the internal standard 2'-HO-tribromodiphenyl ether (2'-HO-BDE-28) spiked to surface water and WSTP effluent samples ranged similarly from 104+/-8% and 91+/-10%, respectively, and method limits of quantification were in the low ppb/high ppt range. However, ESI(-) enhancement was found for both analytes due to sample matrix effects, as indicated by % process efficiencies (a measure of ESI(-) enhancement/suppression), which were in the 111-128% range. We report the first known assessment of triclosan in the Detroit River watershed of the Great Lakes, which preliminarily examined the presence and UV-treatment effects on triclosan in effluent from the major WSTP serving the City of Windsor, Ontario, Canada, and fate in surface waters of the upper Detroit River. Triclosan in WSTP effluent decreased 22% after final UV treatment to a mean concentration of 63 ng/L. Concentrations were further reduced to 4 and 8 ng/L (a >90% reduction) in surface water samples from sites downstream on the Canadian shoreline of the Detroit River, which was due to dilution. Two hydroxylated tribrominated diphenyl ethers, which are structurally similar to triclosan, were also detected in WSTP effluent and surface water samples.
Authors:
Wenyi Hua; Erin R Bennett; Robert J Letcher
Related Documents :
11939538 - Selenium speciation by hplc with tandem mass spectrometric detection.
10818458 - Evaluation of plasma lysophospholipids for diagnostic significance using electrospray i...
16633578 - In vitro biotransformation of an arsenosugar by mouse anaerobic cecal microflora and ce...
15794558 - Simultaneous determination of sildenafil, vardenafil and tadalafil as forbidden compone...
15228118 - Simultaneous derivative spectrophotometric determination of zinc and cadmium with 2-(5-...
23499588 - Detection methods for micrornas in clinic practice.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2004-12-02
Journal Detail:
Title:  Environment international     Volume:  31     ISSN:  0160-4120     ISO Abbreviation:  Environ Int     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-05-24     Completed Date:  2005-09-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7807270     Medline TA:  Environ Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  621-30     Citation Subset:  IM    
Affiliation:
Great Lakes Institute for Environmental Research, University of Windsor, Windsor, Ontario, Canada N9B 3P4.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anti-Infective Agents, Local / analysis*
Chromatography, Liquid
Environmental Monitoring
Mass Spectrometry
Michigan
Rivers
Triclosan / analysis*
Water Pollutants, Chemical / analysis*
Chemical
Reg. No./Substance:
0/Anti-Infective Agents, Local; 0/Water Pollutants, Chemical; 3380-34-5/Triclosan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  "Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular dis...
Next Document:  Arsenic geochemistry and health.