| Trichuris dysentery syndrome: a common cause of chronic iron deficiency anemia in adults in an endemic area (with videos). | |
| | |
MedLine Citation:
|
PMID: 19879568 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: There are few published reports of Trichuris dysentery syndrome (TDS) in children. The disease has not been reported in adults. OBJECTIVE: To report the clinical, colonoscopic, and histologic findings of TDS in adults in an endemic area. DESIGN: Case series. SETTING: Tertiary gastroenterology center. PATIENTS: Eighty-four consecutive adult patients with chronic iron deficiency anemia over a 3-year period were investigated. Ten patients had severe Trichuris trichiura infection and received a diagnosis of TDS. INTERVENTIONS AND MAIN OUTCOME MEASUREMENTS: Colonoscopy and colonic biopsies. Patients received anthelmintic treatment, and their response was assessed. RESULTS: Ten patients with TDS were studied, including 8 female and 2 male patients with a mean (+/- standard deviation) age of 43 (+/- 15.5) years (range 15-65 years) and a hemoglobin level (+/- standard deviation) of 6.0 +/- 1.5 g/dL (range 4-8 g/dL); the duration (+/- standard deviation) of disease was 2.1 +/- 1.1 years (range 1.5-8.5 years). None of the patients had growth retardation, malnutrition, or immunodeficiency. Abdominal symptoms included abdominal pain, diarrhea, and hematochezia in 1 patient. Nine other patients had no abdominal symptoms. Colonoscopy revealed actively motile T. trichiura worms in large numbers in the right colon in 7 patients, in the ileum in 1, in the left colon in 1, and worms carpeting of the whole colonic mucosa in 1. Associated mucosal changes included petechial lesions, blotchy mucosal hemorrhages, and active mucosal oozing. Biopsy of the colon revealed worm segments with a thick outer cuticle. The posterior segment of the worm contained gravid uterus with numerous characteristic T. trichiura eggs. There was paucity of associated mucosal changes in most of the sections. LIMITATIONS: Similar studies in other endemic areas are lacking. CONCLUSION: TDS should be considered in all patients in endemic areas with chronic iron deficiency anemia and/or occult blood loss. |
| | |
Authors:
|
Mohammad S Khuroo; Mehnaaz S Khuroo; Naira S Khuroo |
Related Documents
:
|
11926558 - Diminutive polyps of large bowel should be an early target for endoscopic treatment. 18942638 - Prospective comparison of three bowel preparation regimens: fleet phosphosoda, two-lite... 16003138 - Colonic diverticular disease in a multiracial asian patient population has an ethnic pr... 20579648 - Cap-fitted colonoscopy: a randomized, tandem colonoscopy study of adenoma miss rates. 7091448 - D-amphetamine-induced heterogeneous changes in psychotic behavior in schizophrenia. 22843558 - Increased circulating endothelial microparticles in copd patients: a potential biomarke... |
Publication Detail:
|
Type: Journal Article Date: 2009-10-31 |
Journal Detail:
|
Title: Gastrointestinal endoscopy Volume: 71 ISSN: 1097-6779 ISO Abbreviation: Gastrointest. Endosc. Publication Date: 2010 Jan |
Date Detail:
|
Created Date: 2010-01-28 Completed Date: 2010-04-27 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0010505 Medline TA: Gastrointest Endosc Country: United States |
Other Details:
|
Languages: eng Pagination: 200-4 Citation Subset: IM |
Copyright Information:
|
2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved. |
Affiliation:
|
Digestive Disease Centre, Dr. Khuroo's Medical Clinic, Department of Pathology, Sher-e-Kashmir, Institute of Medical Sciences, Soura, Srinagar, Kashmir, India. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Anemia, Iron-Deficiency / parasitology* Animals Anthelmintics / therapeutic use Chronic Disease Colonoscopy Dysentery / complications, diagnosis*, drug therapy, epidemiology Endemic Diseases* Female Hematinics / therapeutic use Humans Iron Compounds / therapeutic use Male Middle Aged Syndrome Trichuriasis / complications, diagnosis*, drug therapy, epidemiology Trichuris* Video Recording Young Adult |
| Chemical | |
Reg. No./Substance:
|
0/Anthelmintics; 0/Hematinics; 0/Iron Compounds |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Endoscopic partial resection with the unroofing technique for reliable tissue diagnosis of upper GI ...
Next Document: Feasibility of endoscopic transesophageal thoracic sympathectomy (with video).