| Trichosporon beigelii: a life-threatening pathogen in immunocompromised hosts. | |
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MedLine Citation:
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PMID: 10745260 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients undergoing bone marrow transplantation are profoundly immunosuppressed as a result of their intensive myeloablative chemotherapy and are at high risk for opportunistic fungal infections mainly caused by Candida spp and Aspergillus spp. Trichosporon beigelii (T beigelii) has emerged as a life-threatening opportunistic pathogen in granulocytopenic and immunocompromised hosts and there is a marked increase in cases reported in the literature. Response to antifungal agents is poor, mortality is high and immunological recovery is the most important factor for a favorable outcome in patients with trichosporonosis. We present three cases of T. beigelii infection in patients undergoing allogeneic bone marrow transplantation in our center and we review cases described in the literature. |
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Authors:
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B Erer; M Galimberti; G Lucarelli; C Giardini; P Polchi; D Baronciani; D Gaziev; E Angelucci; G Izzi |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bone marrow transplantation Volume: 25 ISSN: 0268-3369 ISO Abbreviation: Bone Marrow Transplant. Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-05-12 Completed Date: 2000-05-12 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8702459 Medline TA: Bone Marrow Transplant Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 745-9 Citation Subset: IM |
Affiliation:
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Divisione di Ematologia e Centro Trapianti Midollo Osseo di Muraglia, Pesaro, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Bone Marrow Transplantation / adverse effects, immunology* Child Critical Illness Female Graft vs Host Disease Humans Immunocompromised Host* Leukemia-Lymphoma, Adult T-Cell / therapy Leukopenia Male Mycoses / etiology*, immunology Transplantation, Homologous Trichosporon* / pathogenicity beta-Thalassemia / therapy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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