| Triacylglycerol synthesis in goat mammary gland. Factors influencing the esterification of fatty acids synthesized de novo. | |
| | |
MedLine Citation:
|
PMID: 6743284 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
ATP alone had no effect on incorporation of fatty acids synthesized de novo and membrane-bound diacylglycerol into triacylglycerol. Combined addition of ATP and Mg2+ totally inhibits incorporation of fatty acids synthesized de novo and stimulated incorporation of membrane-bound diacylglycerol. ATP, Mg2+ and glycerol 3-phosphate stimulate incorporation of fatty acids synthesized de novo into triacylglycerol, but inhibited the incorporation of membrane-bound diacylglycerol. Diacylglycerol generated in situ was shown to be superior to diacylglycerols preloaded on the membrane as substrate for the diacylglycerol acyltransferase. A model is proposed to explain the effect of absorbed exogenous fatty acid on fatty acid synthesis de novo in goat mammary gland. |
| | |
Authors:
|
H O Hansen; I Grunnet; J Knudsen |
Related Documents
:
|
9470174 - Biosynthesis of triacylglycerols containing ricinoleate in castor microsomes using 1-ac... 8407914 - The regulation of phospholipase c-gamma 1 by phosphatidic acid. assessment of kinetic p... 7931124 - Analysis of lung surfactant in the metamorphosing bullfrog (rana catesbeiana). 8144664 - Gtp hydrolysis by adp-ribosylation factor is dependent on both an adp-ribosylation fact... 21485274 - The coloring constituents of scleroderma sinnamariense (sclerodermaceae). 11963884 - Influence of culture conditions on lipopeptide production by bacillus subtilis. |
Publication Detail:
|
Type: In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The Biochemical journal Volume: 220 ISSN: 0264-6021 ISO Abbreviation: Biochem. J. Publication Date: 1984 Jun |
Date Detail:
|
Created Date: 1984-08-15 Completed Date: 1984-08-15 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 2984726R Medline TA: Biochem J Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 521-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acyltransferases
/
metabolism Adenosine Triphosphate / pharmacology Animals Diacylglycerol O-Acyltransferase Diglycerides / metabolism Esterification Fatty Acids / biosynthesis* Female Glycerophosphates / pharmacology Goats Magnesium / pharmacology Mammary Glands, Animal / drug effects, metabolism* Microsomes / drug effects, metabolism Palmitoyl Coenzyme A / pharmacology Pregnancy Triglycerides / biosynthesis* |
| Chemical | |
Reg. No./Substance:
|
0/Diglycerides; 0/Fatty Acids; 0/Glycerophosphates; 0/Triglycerides; 1763-10-6/Palmitoyl Coenzyme A; 56-65-5/Adenosine Triphosphate; 57-03-4/alpha-glycerophosphoric acid; 7439-95-4/Magnesium; EC 2.3.-/Acyltransferases; EC 2.3.1.20/Diacylglycerol O-Acyltransferase |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Photoaffinity labelling of nucleoside-transport proteins in plasma membranes isolated from rat and g...
Next Document: A chromosomal phosphoprotein is preferentially released by mild micrococcal-nuclease digestion.