Document Detail


Triacylglycerol hydroperoxides not detected in pig small intestinal epithelial cells after a diet rich in oxidized triacylglycerols.
MedLine Citation:
PMID:  16028716     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The presence of TAG hydroperoxides in the epithelial cells of the small intestines in growing pigs was studied after they had consumed a diet rich in either nonoxidized or oxidized sunflower seed oil (PV in oils, 1 and 190 mequiv O2/kg, respectively). To obtain molecular-level information on the oxidized TAG structures, a new approach based on TLC and HPLC-electrospray ionization-MS was used in the analysis of the samples. TAG hydroperoxides were not detected in the small intestinal mucosa or adipose tissue of either group, whereas TAG hydroxides, ketones, and epoxides were detected in all samples. The results suggest that dietary TAG hydroperoxides do not lead to the appearance of these molecules in the tissues.
Authors:
Jukka-Pekka Suomela; Markku Ahotupa; Heikki Kallio
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lipids     Volume:  40     ISSN:  0024-4201     ISO Abbreviation:  Lipids     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-07-20     Completed Date:  2006-01-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  United States    
Other Details:
Languages:  eng     Pagination:  349-53     Citation Subset:  IM    
Affiliation:
Department of Biochemistry and Food Chemistry, University of Turku, Finland. jusuom@utu.fi
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MeSH Terms
Descriptor/Qualifier:
Animals
Chromatography, Ion Exchange
Dietary Fats / metabolism*
Intestinal Mucosa / cytology,  metabolism*
Intestine, Small / metabolism*
Lipid Peroxidation / physiology*
Male
Swine
Triglycerides / chemistry,  metabolism*
Chemical
Reg. No./Substance:
0/Dietary Fats; 0/Triglycerides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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