Document Detail


Trends of stomach cancer mortality in eastern Asia in 1950-2004: Comparative study of Japan, Hong Kong and Singapore using age, period and cohort analysis.
MedLine Citation:
PMID:  21425256     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
To characterize the temporal trends of stomach cancer mortality in Eastern Asia and to better interpret the causes of the trends, we performed age, period and cohort analysis (APC analysis) on the mortality rates in Japan, Hong Kong and Singapore during 1950-2004, as well as the rates in the US as a control population. For the APC analysis, Holford's approach was used to avoid the identification problem. Age-standardized mortality rates (ASMR) decreased consistently in all four areas during the observation period in both males and females. Japan had the highest ASMR in both sexes, followed by Singapore, Hong Kong, and the US, but the differences in ASMR among the four areas diminished with time. The results of APC analysis suggested that the decreasing mortality rates in Eastern Asia were caused by the combination of decreasing cohort effect since the end of the 1800s and decreasing period effect from the 1950s. The US showed similar results, but its decreases in the period and cohort effect preceded those of Eastern Asia. Possible causes for the decrease in the cohort effect include improvement in the socioeconomic conditions during childhood and a decrease in the prevalence of H. pylori infection, while possible causes for the decrease in the period effect include a decrease in dietary salt intake and improvements in cancer detection and treatment. These findings may help us to predict future changes in the mortality rates of stomach cancer.
Authors:
Masahiro Tanaka; Enbo Ma; Hideo Tanaka; Akiko Ioka; Toshitaka Nakahara; Hideto Takahashi
Related Documents :
19264126 - Prostate tumor-initiating cells: a new target for telomerase inhibition therapy?
15176976 - The three-dimensional organization of telomeres in the nucleus of mammalian cells.
21707046 - Isolation and biological evaluation of jatrophane diterpenoids from euphorbia dendroides.
11228226 - Ultrastructural observations of enzymatically treated human blastocysts: zona-free blas...
10615296 - Study of cancer incidence among 8530 male workers in eight norwegian plants producing f...
22341926 - Roles of hif-1α in a novel optical orthotopic spontaneous metastatic bladder cancer an...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-21
Journal Detail:
Title:  International journal of cancer. Journal international du cancer     Volume:  -     ISSN:  1097-0215     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0042124     Medline TA:  Int J Cancer     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 UICC.
Affiliation:
Department of Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Diseases. tanaka-ma2@mc.pref.osaka.jp.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  D-4F, an apoA-I mimetic peptide, inhibits proliferation and tumorigenicity of epithelial ovarian can...
Next Document:  Helicobacter pylori infection as an independent prognostic factor for locally advanced gastric cance...