| Trends and morbidity associated with oxytocin use in labour in nulliparas at term. | |
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MedLine Citation:
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PMID: 22384940 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AIM: To determine the trends in oxytocin use at a population level within New South Wales and to assess the maternal and neonatal morbidities associated with the use of oxytocin. METHODS: Trends in oxytocin use were assessed for women in NSW who were nulliparas at term with a singleton, cephalic fetus between 1998 and 2008. Maternal and neonatal morbidities were assessed in 2007-2008 using linked hospital and birth data with regression analysis. Oxytocin was also assessed by indication for use being either induction or augmentation of labour. RESULTS: The overall use of oxytocin increased from 10 291 (36.5%) of births in 1998 to 14 440 (45.4%) of births in 2008 (P < 0.0001) with the increase entirely because of the increased use for induction of labour. The use of oxytocin was associated with an increase in regional analgesia (65 to 22%), instrumental delivery (21 to 18%) and caesarean section (29 to 14%) as compared to women who did not receive oxytocin in labour. Oxytocin was also associated with an increase in severe maternal adjusted odds ratios ((aOR) 1.48, 95% CI 1.30-1.68) and neonatal morbidity (aOR 1.29, 95% CI 1.17-1.41). This increase in morbidity was maintained when both augmentation and induction were assessed separately. CONCLUSION: Oxytocin has an important role in the management of labour. However, its use should be carefully monitored with standardised treatment regimes to minimise maternal and neonatal morbidity. |
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Authors:
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Sarah L Buchanan; Jillian A Patterson; Christine L Roberts; Jonathan M Morris; Jane B Ford |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-5 |
Journal Detail:
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Title: The Australian & New Zealand journal of obstetrics & gynaecology Volume: - ISSN: 1479-828X ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0001027 Medline TA: Aust N Z J Obstet Gynaecol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 The Authors Australian and New Zealand Journal of Obstetrics and Gynaecology © 2012 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists. |
Affiliation:
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Royal North Shore Hospital, University of Sydney, Sydney, NSW, Australia. |
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