Document Detail

Trends and innovations in industrial biocatalysis for the production of fine chemicals.
MedLine Citation:
PMID:  15357999     Owner:  NLM     Status:  MEDLINE    
Biocatalysis has become an established technology for the industrial manufacture of fine chemicals. In recent years, a multitude of chemical companies have embraced biocatalysis for the manufacture of desired stereoisomers, and new or improved methods for the synthesis of enantiomerically pure alpha- and beta-amino acids, amines, amides, peptides, nitriles, alcohols, organic acids and epoxides have emerged. Furthermore, the selectivity and mild operational conditions of biocatalysts are increasingly applied in industry to modify complex target molecules. These recent innovations in the manufacture of industrial fine chemicals using biocatalysis are discussed from an industrial perspective.
Sven Panke; Martin Held; Marcel Wubbolts
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in biotechnology     Volume:  15     ISSN:  0958-1669     ISO Abbreviation:  Curr. Opin. Biotechnol.     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-09-10     Completed Date:  2005-02-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9100492     Medline TA:  Curr Opin Biotechnol     Country:  England    
Other Details:
Languages:  eng     Pagination:  272-9     Citation Subset:  IM    
DSM Research Campus Geleen, Advanced Synthesis & Catalysis, PO Box 18, 6160 MD Geleen, The Netherlands.
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MeSH Terms
Alcohols / metabolism
Amines / metabolism
Amino Acids / biosynthesis*
Carbohydrates / biosynthesis
Chemical Industry / methods*,  statistics & numerical data,  trends*
Enzymes / chemistry*,  metabolism*
Hydrolases / metabolism
Industrial Microbiology / methods,  statistics & numerical data,  trends
Oxidoreductases / biosynthesis
Patents as Topic / statistics & numerical data*
Reg. No./Substance:
0/Alcohols; 0/Amines; 0/Amino Acids; 0/Carbohydrates; 0/Enzymes; EC 1.-/Oxidoreductases; EC 3.-/Hydrolases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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