Document Detail


Trends and innovations in industrial biocatalysis for the production of fine chemicals.
MedLine Citation:
PMID:  15357999     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Biocatalysis has become an established technology for the industrial manufacture of fine chemicals. In recent years, a multitude of chemical companies have embraced biocatalysis for the manufacture of desired stereoisomers, and new or improved methods for the synthesis of enantiomerically pure alpha- and beta-amino acids, amines, amides, peptides, nitriles, alcohols, organic acids and epoxides have emerged. Furthermore, the selectivity and mild operational conditions of biocatalysts are increasingly applied in industry to modify complex target molecules. These recent innovations in the manufacture of industrial fine chemicals using biocatalysis are discussed from an industrial perspective.
Authors:
Sven Panke; Martin Held; Marcel Wubbolts
Related Documents :
3733929 - Use of pico-tag methodology in the chemical analysis of peptides with carboxyl-terminal...
9043659 - Synthesis of characteristic lipopeptides of the human n-ras protein and their evaluatio...
19904369 - Solid-phase synthesis of protected alpha-amino phosphonic acid oligomers.
347399 - The identification of the trna substrates for the supk trna methylase.
649259 - Solid-phase peptide synthesis using mild base cleavage of n alpha-fluorenylmethyloxycar...
12714079 - The mechanism of the dissolution, spray and deposition technique--a novel infrared samp...
17173469 - Efficacy and safety of hyaluronic acid in the management of acute wounds.
12435169 - Development and characterization of darbepoetin alfa.
8199429 - Biochemical and functional approaches to study of fatty acid requirements for very prem...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in biotechnology     Volume:  15     ISSN:  0958-1669     ISO Abbreviation:  Curr. Opin. Biotechnol.     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-09-10     Completed Date:  2005-02-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9100492     Medline TA:  Curr Opin Biotechnol     Country:  England    
Other Details:
Languages:  eng     Pagination:  272-9     Citation Subset:  IM    
Affiliation:
DSM Research Campus Geleen, Advanced Synthesis & Catalysis, PO Box 18, 6160 MD Geleen, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Alcohols / metabolism
Amines / metabolism
Amino Acids / biosynthesis*
Biotransformation
Carbohydrates / biosynthesis
Catalysis*
Chemical Industry / methods*,  statistics & numerical data,  trends*
Enzymes / chemistry*,  metabolism*
Hydrolases / metabolism
Industrial Microbiology / methods,  statistics & numerical data,  trends
Oxidoreductases / biosynthesis
Patents as Topic / statistics & numerical data*
Chemical
Reg. No./Substance:
0/Alcohols; 0/Amines; 0/Amino Acids; 0/Carbohydrates; 0/Enzymes; EC 1.-/Oxidoreductases; EC 3.-/Hydrolases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Non-peptide oxytocin agonists.
Next Document:  Enantioselective biocatalysis optimized by directed evolution.