| Trends in severity of hospitalized myocardial infarction: the atherosclerosis risk in communities (ARIC) study, 1987-1994. | |
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MedLine Citation:
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PMID: 10783222 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Declining mortality rates of coronary heart disease in the United States could be attributable to declining incidence, declining severity, and/or improvements in treatment. METHODS: We examined trends in severity of patients hospitalized for myocardial infarction to characterize its contribution to this decline by using data from the Atherosclerosis Risk in Communities (ARIC) study. RESULTS: No significant change in the proportion having systolic blood pressure <100 mm Hg or an abnormal pulse at presentation was noted. The proportion with ST-segment elevation on the initial electrocardiogram increased 10% per year (P <.001), and the proportion with a diagnostic or evolving diagnostic electrocardiogram abnormality increased 4% per year (P <.01); the proportion that had a new Q-wave infarction develop remained unchanged. The mean peak creatine kinase level decreased 5% per year (P <.001), the proportion with abnormal enzyme levels decreased 10% per year (P <.001), and the proportion that met criteria for definite myocardial infarction decreased 4% per year (P <.05). The proportion that had cardiogenic shock decreased 10.9% per year (P <. 01), but the proportion that had an acute episode of congestive heart failure was stable. CONCLUSIONS: With stable hemodynamic indicators, worsening electrocardiographic indicators, and improving enzymatic indicators, these results provide mixed support for decreases in the severity of myocardial infarction. |
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Authors:
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D C Goff; G Howard; C H Wang; A R Folsom; W D Rosamond; L S Cooper; L E Chambless |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American heart journal Volume: 139 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 2000 May |
Date Detail:
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Created Date: 2000-05-30 Completed Date: 2000-05-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 874-80 Citation Subset: AIM; IM |
Affiliation:
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Wake Forest University School of Medicine, Winston-Salem, NC 27157-1063, USA. dgoff@wfubmc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Coronary Artery Disease / diagnosis, mortality*, therapy Female Hospitalization / trends* Humans Male Middle Aged Myocardial Infarction / diagnosis, mortality*, therapy Population Surveillance Risk Assessment Severity of Illness Index Survival Rate United States / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
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N01HC55015/HC/NHLBI NIH HHS; N01HC55016/HC/NHLBI NIH HHS; N01HC55018/HC/NHLBI NIH HHS |
| Comments/Corrections | |
Comment In:
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Am Heart J. 2000 May;139(5):767-70
[PMID:
10783207
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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