Document Detail

Trends in risk factors and etiology of 606 cases of infective endocarditis over 23 years (1984-2006) in slovakia.
MedLine Citation:
PMID:  17434830     Owner:  NLM     Status:  MEDLINE    
The aim of this study was to assess trends in risk factors, etiology, outcome and treatment strategies for endocarditis over 23 years in Slovakia. A prospective survey of 606 cases of infective endocarditis (IE) was conducted from 1984-2006. Rheumatic fever as well as previous dental surgery showed decreasing trends within the last 23 years. Also embolic complications of IE declined along with increasing rates of surgically treated patients. No significant changes in etiology were detected apart from the fact that culture-negative endocarditis increased from 10.7% to 55.4% between 1998-2001. Surgically treated patients increased from 22.7% (1984-1990) to 50.1% (2002-2006) and mortality dramatically decreased from 26.7% (1984-1990) to 5.3% (2002-2006). Staphylococcus aureus and coagulase-negative staphylococci were the leading causes (22.4% - 48%) followed by viridans streptococci (12.2%-18.2%) were a relatively stable trend over 23 years of IE in Slovakia.
V Hricak; B Liska; J Kovackova; J Mikusova; V Fischer; J Kovacik; M Karvaj; R Jurco; A Ondrusova; E Kalavsky; P Marks; P Beno; V Krcmery
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of chemotherapy (Florence, Italy)     Volume:  19     ISSN:  1120-009X     ISO Abbreviation:  J Chemother     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-16     Completed Date:  2007-06-14     Revised Date:  2009-08-04    
Medline Journal Info:
Nlm Unique ID:  8907348     Medline TA:  J Chemother     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  198-202     Citation Subset:  IM    
National Institute of Cardiovascular Diseases, Bratislava, Slovakia.
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MeSH Terms
Endocarditis, Bacterial / epidemiology*,  etiology,  mortality,  therapy
Middle Aged
Prospective Studies
Risk Factors
Treatment Outcome

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