Document Detail


Trends in psychotropic drug prescribing in Norwegian nursing homes from 1997 to 2009: a comparison of six cohorts.
MedLine Citation:
PMID:  23147389     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Psychotropic drugs are extensively prescribed for the treatment of neuropsychiatric symptoms, despite modest efficacy and severe side effects. AIMS: We examined trends in psychotropic drug prescribing in Norwegian nursing homes from 1997 to 2009, in order to gain insight in practice development. METHODS: The study is a secondary data analysis of six cross-sectional nursing home studies conducted between 1997 and 2009. Patients aged >65 years were included. We compared the prevalence of psychotropic drugs (antipsychotics, anxiolytics, hypnotics, and antidepressants). Associations between prescription of psychotropics, and patients' age, gender, type of ward, and year of data collection were examined by univariate analysis and logistic regression. RESULTS: Altogether, 7 661 patients (mean age 85.2 years, 72.6% women) were included. Prevalence of all psychotropic drugs combined increased from 57.6% to 70.5%, anxiolytics from 14.9% to 21.9%, hypnotics from 14.5% to 22.9%, and antidepressants from 31.5% to 50.9%. Prevalence of antipsychotics varied between extremes 21.1% and 25.6%. Less prescribing of older drugs was exceeded by an increase in newer drug types. Concomitant prescribing of two or more psychotropic drugs increased from 21% to 33%. Predictors of psychotropic drugs were female gender (except antipsychotics), as well as age <80 years, and residency in special care units (except hypnotics). CONCLUSIONS: Prescribing of psychotropic drugs in nursing homes has increased considerably, especially regarding antidepressants. Explanations for this trend need to be further explored. Copyright © 2012 John Wiley & Sons, Ltd.
Authors:
Sabine Ruths; Pernille Hegre Sørensen; Oyvind Kirkevold; Bettina S Husebø; Kjell Krüger; Kjell H Halvorsen; Geir Selbaek
Related Documents :
23329709 - Drug-induced immune thrombocytopenia due to moxifloxacin.
6749369 - Plasma protein binding of drugs in pregnancy.
53059 - Binding of tubocurarine to specific serum protein fractions.
15094329 - Nitric oxide release and distribution following oral and intraperitoneal administration...
18520949 - Effects of atazanavir/ritonavir or fosamprenavir/ritonavir on the pharmacokinetics of r...
334679 - Plasma levels of di-no-propylacetate and clonazepam in epileptic patients.
23066179 - Solubility enhancement of benfotiamine, a lipid derivative of thiamine by solid dispers...
8983169 - Effects of experimental dicrocoeliosis on oxidative drug metabolism in hamster liver.
7472809 - Molecular mechanism of drug photosensitization. part 6. photohaemolysis sensitized by t...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-13
Journal Detail:
Title:  International journal of geriatric psychiatry     Volume:  -     ISSN:  1099-1166     ISO Abbreviation:  Int J Geriatr Psychiatry     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710629     Medline TA:  Int J Geriatr Psychiatry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 John Wiley & Sons, Ltd.
Affiliation:
Research Unit for General Practice, Uni Health/Uni Research, Bergen, Norway; Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway. sabine.ruths@isf.uib.no.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Do Depression and Educational Attainment Mediate the Association between Ethnicity and Dementia?.
Next Document:  Combined and interactive effects of global climate change and toxicants on populations and communiti...