| Trends in the prevalence of transfusion-transmissible infections among blood donors in Albania. | |
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MedLine Citation:
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PMID: 21141446 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The objective of this study is to determine the trend of transfusion transmitted infection in blood donors. METHODS: In this study 52727 blood donors were retrospectively evaluated for markers of hepatitis B, C, HIV(1/2), and syphilis. To screen the blood donors for HIV(1/2)(HIV(1/2) Ag/Ab COMBO, ABBOTT Laboratory, Delkenheim, Germany), the microparticle enzyme immunoassay (MEIA) method was used. For HBsAg and anti-HCV third generation MEIA kits (ABBOTT Laboratory, Delkenheim, Germany) were used and for the syphilis RPR test the Biokit SA (Barcelona, Spain) was used. RESULTS: A total of 52,727 donors were tested within the five year period, of which 15 (0.03%), 3531 (6.7%), 323 (0.6%), and 35 (0.07%) were positive for HIV, HBV, HCV, and syphilis, respectively. The prevalence of TTI in blood donors was 7.4%. It increased steadily from 5.1% in 2004 to 8.3% in 2006, stayed in same level in 2007, and decreased to 8.1% in 2008. Distribution of transfusion-transmissible infection (TTI) based on donor status was 13.8% in first time commercial remunerated blood donors, 9.4% in first time voluntary blood donors, and 9.7% in family replacement blood donors. CONCLUSIONS: Our results in this study showed that family replacement donors are more likely to transmit transfusion-transmissible infections (TTIs) than voluntary donors, but are safer than commercial blood donors. So blood transfusion services should work on replacement of family blood donors with voluntary non-remunerated blood donors. |
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Authors:
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Vjollca Durro; Andi Koraqi; Sadik Saliasi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical laboratory Volume: 56 ISSN: 1433-6510 ISO Abbreviation: Clin. Lab. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-12-13 Completed Date: 2011-01-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9705611 Medline TA: Clin Lab Country: Germany |
Other Details:
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Languages: eng Pagination: 591-5 Citation Subset: IM |
Affiliation:
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Hospital Directory Ministry of Health, Albania. vdurro@moh.gov.al |
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| MeSH Terms | |
Descriptor/Qualifier:
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Albania
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epidemiology Antibodies, Bacterial / blood Antibodies, Viral / blood Blood Donors / statistics & numerical data* Blood-Borne Pathogens / isolation & purification* Chi-Square Distribution Communicable Diseases / blood*, epidemiology* Disease Transmission, Infectious Enzyme-Linked Immunosorbent Assay HIV / isolation & purification Hepacivirus / isolation & purification Hepatitis B Surface Antigens / blood Hepatitis B virus / isolation & purification Humans Retrospective Studies Syphilis / blood, epidemiology Treponema pallidum / isolation & purification Virus Diseases / blood, epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial; 0/Antibodies, Viral; 0/Hepatitis B Surface Antigens |
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