Document Detail

Trends in the prevalence and incidence of diabetes in the UK: 1996-2005.
MedLine Citation:
PMID:  19240084     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: To estimate the incidence and prevalence of type 1 and type 2 diabetes in the UK general population from 1996 to 2005. METHODS: Using the Health Improvement Network database, patients with type 1 or type 2 diabetes were identified who were 10-79 years old between 1996 and 2005. Prevalent cases (n = 49 999) were separated from incident cases (n = 42 642; type 1 = 1256, type 2 = 41 386). Data were collected on treatment patterns in incident cases, and on body mass index in prevalent and incident cases. RESULTS: Diabetes prevalence increased from 2.8% in 1996 to 4.3% in 2005. The incidence of diabetes in the UK increased from 2.71 (2.58-2.85)/1000 person-years in 1996 to 4.42 (4.32-4.53)/1000 person-years in 2005. The incidence of type 1 diabetes remained relatively constant throughout the study period; however, the incidence of type 2 diabetes increased from 2.60 (2.47-2.74)/1000 person-years in 1996 to 4.31 (4.21-4.42)/1000 person-years in 2005. Between 1996 and 2005, the proportion of individuals newly diagnosed with type 2 diabetes who were obese increased from 46% to 56%. Treatment with metformin increased across the study period, while treatment with sulphonylureas decreased. CONCLUSIONS: The prevalence and incidence of type 2 diabetes have increased in the UK over the past decade. This might be primarily explained by the changes in obesity prevalence. Also, there was a change in drug treatment pattern from sulphonylureas to metformin.
E L Massó González; S Johansson; M-A Wallander; L A García Rodríguez
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-02-24
Journal Detail:
Title:  Journal of epidemiology and community health     Volume:  63     ISSN:  1470-2738     ISO Abbreviation:  J Epidemiol Community Health     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-20     Completed Date:  2010-03-12     Revised Date:  2010-08-31    
Medline Journal Info:
Nlm Unique ID:  7909766     Medline TA:  J Epidemiol Community Health     Country:  England    
Other Details:
Languages:  eng     Pagination:  332-6     Citation Subset:  IM    
Spanish Centre for Pharmacoepidemiological Research, Almirante 28, Madrid, Spain.
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MeSH Terms
Age Distribution
Diabetes Mellitus, Type 1 / drug therapy,  epidemiology*
Diabetes Mellitus, Type 2 / drug therapy,  epidemiology*
Epidemiologic Methods
Great Britain / epidemiology
Hypoglycemic Agents / therapeutic use
Middle Aged
Sex Distribution
Young Adult
Reg. No./Substance:
0/Hypoglycemic Agents
Erratum In:
J Epidemiol Community Health. 2009 Oct;63(10):864

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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